IGUANe: A 3D generalizable CycleGAN for multicenter harmonization of brain MR images

• Published in: Medical image analysis Vol. 99; p. 103388
• Main Authors: Roca, Vincent, Kuchcinski, Grégory, Pruvo, Jean-Pierre, Manouvriez, Dorian, Lopes, Renaud
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2025
• Series: Med Image Anal
• Subjects: Adult; Aged; Alzheimer; Alzheimer Disease - diagnostic imaging; Brain - diagnostic imaging; Brain age; Brain MRI; Deep Learning; Harmonization; Humans; Image synthesis; Imaging, Three-Dimensional - methods; Life Sciences; Magnetic Resonance Imaging - methods; Middle Aged; Multisite; Image synthesis; Brain MRI; Alzheimer; Brain age; Harmonization; Multisite

In MRI studies, the aggregation of imaging data from multiple acquisition sites enhances sample size but may introduce site-related variabilities that hinder consistency in subsequent analyses. Deep learning methods for image translation have emerged as a solution for harmonizing MR images across si...