Biological characterization of highly pathogenic avian influenza H5N1 viruses that infected humans in Egypt in 2014-2015

• Published in: Archives of virology Vol. 162; no. 3; pp. 687 - 700
• Main Authors: El-Shesheny, Rabeh, Mostafa, Ahmed, Kandeil, Ahmed, Mahmoud, Sara H., Bagato, Ola, Naguib, Amel, Refaey, Samir El, Webby, Richard J., Ali, Mohamed A., Kayali, Ghazi
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.03.2017; Springer Nature B.V
• Subjects: animal pathogens; Animals; Avian flu; avian influenza; bioassays; Biomedical and Life Sciences; Biomedicine; Birds; chicken eggs; Chickens; Disease Outbreaks; Egypt; Egypt - epidemiology; Epidemics; Fatalities; Humans; Infections; Infectious Diseases; Influenza A virus; Influenza A Virus, H5N1 Subtype - classification; Influenza A Virus, H5N1 Subtype - genetics; Influenza A Virus, H5N1 Subtype - isolation & purification; Influenza A Virus, H5N1 Subtype - pathogenicity; Influenza, Human - epidemiology; Influenza, Human - virology; Medical Microbiology; monitoring; nucleotide sequences; Original Article; pandemic; Phylogenetics; Phylogeny; Poultry; Poultry Diseases - epidemiology; Poultry Diseases - virology; Public health; receptors; sialic acid; Vaccines; Virology; Virulence; Viruses; zoonoses; United States > US; Cairo Egypt; Egypt; Amantadine; Hemagglutination Inhibition; Highly Pathogenic Avian Influenza; H5N1 Virus; Influenza

Highly pathogenic avian influenza (HPAI) H5N1 influenza viruses emerged as a human pathogen in 1997 with expected potential to undergo sustained human-to-human transmission and pandemic viral spread. HPAI H5N1 is endemic in Egyptian poultry and has caused sporadic human infection. The first outbreak...