Acetylation of intrinsically disordered regions regulates phase separation - Saito, Makoto; Hess, Daniel; Eglinger, Jan; Fritsch, Anatol W.; Kreysing, Moritz; Weinert, Brian T.; Choudhary, Chunaram; Matthias, Patrick (Nature chemical biology, 2019)
Keywords: 631/45; 631/80; 631/92/458; 631/92/475; Acetylation; Amyotrophic lateral sclerosis; Animals; Biochemical Engineering; Biochemistry; Biology; Bioorganic Chemistry; Catalytic Domain; Cell Biology; Chemistry; Chemistry and Materials Science; Chemistry/Food Science; Cytoplasmic Granules - metabolism; Deacetylation; DEAD-box RNA Helicases - metabolism; DNA helicase; Gene Knockout Techniques; Histone Deacetylase 6 - metabolism; Humans; Intrinsically Disordered Proteins - chemistry; Intrinsically Disordered Proteins - metabolism; Liquid phases; Lysine; Lysine - metabolism; Mice; Models, Theoretical; Mutation; Organelles; Osmotic Pressure; Phase separation; Proteins; Ribonucleic acid; RNA; RNA helicase; RNA Helicases - chemistry; RNA Helicases - genetics; RNA Helicases - metabolism; Substrates