Activity of glutathione S-transferase and its π isoenzyme in the context of single nucleotide polymorphism in the GSTP1 gene (rs1695) and tobacco smoke exposure in the patients with acute pancreatitis and healthy subjects

• Published in: Biomedicine & pharmacotherapy Vol. 140; p. 111589
• Main Authors: Ściskalska, Milena, Milnerowicz, Halina
• Format: Journal Article
• Language: English
• Published: Elsevier Masson SAS 01.08.2021
• Subjects: Glutathione S-transferase; GSTP1; Pancreatitis; rs1695; Single nucleotide polymorphism; Smoking; GSTP1; Pancreatitis; GST; MDA; AP; GST-π; SNP; rs1695; hsCRP; Single nucleotide polymorphism; Glutathione S-transferase; GSH; Smoking

Oxidative stress associated with the course of acute pancreatitis (AP) can cause changes in the involvement of antioxidants, which can result in the increased production of free radicals with pro-inflammatory potential. Through its noncatalytic activity, the glutathione S-transferase and its π isoen...