Photothermal-modulated drug release from a composite hydrogel based on silk fibroin and sodium alginate

• Published in: European Polymer Journal Vol. 146; p. 110267
• Main Authors: Niu, Chunqing, Liu, Xinyu, Wang, Yiyu, Li, Xiang, Shi, Jian
• Format: Journal Article
• Language: English; Japanese
• Published: Oxford Elsevier Ltd 05.03.2021; Elsevier BV
• Subjects: Composite materials; Controlled release; Drug delivery systems; Drug release; Hydrogels; Modulus of elasticity; Near infrared radiation; NIR responsive hydrogels; Polymers; Pore size; Porosity; Radiation effects; Scanning electron microscopy; Serum albumin; Silk fibroin; Sodium alginate; Stiffness; Drug release; Silk fibroin; Sodium alginate; NIR responsive hydrogels

[Display omitted] •A NIR-responsive hydrogel was developed via combination of a SF/SA gel and ICG.•The hydrogel exhibited significant photothermal effects after NIR irradiation.•Drug release profiles from the gels can be controlled by NIR irradiation. In order to realize effective controlled release...