Viscoelastic point-of-care testing to assist with the diagnosis, management and monitoring of haemostasis: a systematic review and cost-effectiveness analysis

• Published in: Health technology assessment (Winchester, England) Vol. 19; no. 58; pp. 1 - 228
• Main Authors: Whiting, Penny, Al, Maiwenn, Westwood, Marie, Ramos, Isaac Corro, Ryder, Steve, Armstrong, Nigel, Misso, Kate, Ross, Janine, Severens, Johan, Kleijnen, Jos
• Format: Journal Article
• Language: English
• Published: England NIHR Journals Library 01.07.2015
• Subjects: Blood Coagulation Disorders - diagnosis; Blood Coagulation Disorders - physiopathology; cardiac surgery; Cost-Benefit Analysis; cost-effectiveness; diagnosis; haemostasis; Hemostasis - physiology; Humans; management; monitoring; point-of-care testing; Point-of-Care Testing - economics; post-partum haemorrhage; standard laboratory tests; systematic review; Thrombelastography - economics; Thrombelastography - methods; transfusion; trauma-induced coagulopathy; viscoelastic

Patients with substantive bleeding usually require transfusion and/or (re-)operation. Red blood cell (RBC) transfusion is independently associated with a greater risk of infection, morbidity, increased hospital stay and mortality. ROTEM (ROTEM® Delta, TEM International GmbH, Munich, Germany; www.rot...