Adaptive evolution of microalgae Schizochytrium sp. under high salinity stress to alleviate oxidative damage and improve lipid biosynthesis

• Published in: Bioresource technology Vol. 267; pp. 438 - 444
• Main Authors: Sun, Xiao-Man, Ren, Lu-Jing, Bi, Zhi-Qian, Ji, Xiao-Jun, Zhao, Quan-Yu, Huang, He
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.11.2018
• Subjects: Adaptive evolution; antioxidant activity; Antioxidant capacity; biosynthesis; carbon metabolism; cell growth; Comparative transcriptomic analysis; evolutionary adaptation; fatty-acid synthase; gene expression regulation; genes; lipids; microalgae; Oxidative stress; polyketide synthases; reactive oxygen species; salinity; salt stress; Schizochytrium; Schizochytrium sp; transcriptomics; Adaptive evolution; Antioxidant capacity; Oxidative stress; Schizochytrium sp; Comparative transcriptomic analysis

•Antioxidant enzymes were taken into account in a novel strain evaluation system.•Adaptive evolution under high salinity improves cell growth and lipid production.•Lipid productivity of evolved strain was increased by 1.96-fold.•Evolved strain showed a significant drop in the ROS and MDA levels.•The...