Trans-ethnic study confirmed independent associations of HLA-A02:06 and HLA-B44:03 with cold medicine-related Stevens-Johnson syndrome with severe ocular surface complications - Ueta, Mayumi; Kannabiran, Chitra; Wakamatsu, Tais Hitomi; Kim, Mee Kum; Yoon, Kyung-Chul; Seo, Kyoung Yul; Joo, Choun-Ki; Sangwan, Virender; Rathi, Varsha; Basu, Sayan; Shamaila, Almas; Lee, Hyo Seok; et al. (Scientific reports, 2014)
Keywords: 45; 692/308/2056; 692/499; Adolescent; Adult; Alleles; Anti-inflammatory agents; Anti-Inflammatory Agents, Non-Steroidal - adverse effects; Brazil; Child; Cold remedies; Dry Eye Syndromes - ethnology; Dry Eye Syndromes - etiology; Dry Eye Syndromes - genetics; Dry Eye Syndromes - immunology; Epithelium, Corneal - immunology; Epithelium, Corneal - pathology; Ethnic Groups; Female; Gene Frequency; Histocompatibility antigen HLA; HLA-A2 Antigen - genetics; HLA-A2 Antigen - immunology; HLA-B44 Antigen - genetics; HLA-B44 Antigen - immunology; Humanities and Social Sciences; Humans; India; Inflammation; Male; Middle Aged; Minority & ethnic groups; Mucosa; Multi-Ingredient Cold, Flu, and Allergy Medications - adverse effects; multidisciplinary; Nonsteroidal anti-inflammatory drugs; Republic of Korea; Retinal Pigment Epithelium - immunology; Retinal Pigment Epithelium - pathology; Risk Factors; Science; Science (multidisciplinary); Skin; Skin diseases; Stevens-Johnson syndrome; Stevens-Johnson Syndrome - ethnology; Stevens-Johnson Syndrome - etiology; Stevens-Johnson Syndrome - genetics; Stevens-Johnson Syndrome - immunology; Toxic epidermal necrolysis; Trichiasis - ethnology; Trichiasis - etiology; Trichiasis - genetics; Trichiasis - immunology; Brazil; Republic of Korea; India