Immobilization of phenol-containing molecules on self-assembled monolayers on gold via surface chemistry

• Published in: Colloids and surfaces, B, Biointerfaces Vol. 173; pp. 164 - 170
• Main Authors: Hwang, Hye-Jeong, Choi, Inseong, Kim, Young-Jin, Kim, Young-Kwan, Yeo, Woon-Seok
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2019
• Subjects: anti-inflammatory activity; azides; Azides - chemistry; Carbodiimides - chemistry; carboxylic acids; Carboxylic Acids - chemistry; Click Chemistry - methods; condensation reactions; Cycloaddition Reaction - methods; flavanones; Flavanones - chemistry; gold; Gold - chemistry; Immobilization; Mannich reaction; moieties; Molecular Structure; Naphthols - chemistry; phenol; Phenol-containing molecules; Phenols - chemistry; Self-assembled monolayers; Sulfhydryl Compounds - chemistry; Surface chemistry; Surface Properties; thiols; tyrosine; Tyrosine - chemistry; Immobilization; Self-assembled monolayers; Mannich reaction; Surface chemistry; Phenol-containing molecules

[Display omitted] •The Mannich reaction was used to functionalize phenolic molecules permitting their surface immobilization.•The strategy did not compromise the phenol functionality and the biological activity of the immobilized molecules.•The modification and the surface immobilization was confirm...