Transfusion-Transmitted Dengue and Associated Clinical Symptoms During the 2012 Epidemic in Brazil

• Published in: The Journal of infectious diseases Vol. 213; no. 5; pp. 694 - 702
• Main Authors: Sabino, Ester C., Loureiro, Paula, Lopes, Maria Esther, Capuani, Ligia, McClure, Christopher, Chowdhury, Dhuly, Di-Lorenzo-Oliveira, Claudia, Oliveira, Lea C., Linnen, Jeffrey M., Lee, Tzong-Hae, Gonçalez, Thelma, Brambilla, Donald, Kleinman, Steve, Busch, Michael P., Custer, Brian
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.03.2016
• Series: Editor's choice
• Subjects: Blood Donors; Brazil - epidemiology; Dengue - epidemiology; Dengue - transmission; Dengue virus; Dengue Virus - isolation & purification; Epidemics; Humans; Major and Brief Reports; RNA, Viral - blood; RNA, Viral - isolation & purification; Transfusion Reaction; VIRUSES; Brazil, Pernambuco, Recife; Brazil, Rio de Janeiro; NAT; transfusion-transmission; dengue; clinical symptoms

Background. A linked donor-recipient study was conducted during epidemics in 2 cities in Brazil to investigate transfusion-transmitted (TT) dengue virus (DENV) by DENV RNA–positive donations. Methods. During February–June 2012, samples were collected from donors and recipients and retrospectively te...