Semen preparation methods and sperm telomere length: density gradient centrifugation versus the swim up procedure

• Published in: Scientific reports Vol. 6; no. 1; p. 39051
• Main Authors: Zhao, Feifei, Yang, Qingling, Shi, Senlin, Luo, Xiaoyan, Sun, Yingpu
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.12.2016; Nature Publishing Group
• Subjects: 38/77; 692/699/2732/1577; 692/699/2732/2731; Adult; Centrifugation; Centrifugation, Density Gradient; Deoxyribonucleic acid; DNA; DNA Fragmentation; Humanities and Social Sciences; Humans; Male; Motility; multidisciplinary; Reactive oxygen species; Science; Semen; Semen - cytology; Semen Analysis; Sperm; Sperm Motility - physiology; Spermatozoa - cytology; Telomere - metabolism; Telomere Homeostasis; Telomeres
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/srep39051

Previous studies have shown that both density gradient centrifugation (DGC) and swim up (SU) procedures can select spermatozoa with longer telomeres for assisted reproduction techniques (ART). However, it is unknown which approach is more effective. The aim of the present study was to compare the ef...