Gonadotropin-inhibitory hormone in teleosts: New insights from a basal representative, the eel

• Published in: General and comparative endocrinology Vol. 287; p. 113350
• Main Authors: Maugars, G., Pasquier, J., Atkinson, C., Lafont, A.-G., Campo, A., Kamech, N., Lefranc, B., Leprince, J., Dufour, S., Rousseau, K.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2020; Elsevier
• Subjects: Anguilla; Animals; Eels; Female; GnIH; GnRH-R; Gonadotropin subunits; Gonadotropin-Releasing Hormone; Gonadotropin-Releasing Hormone - antagonists & inhibitors; Life Sciences; NPVF; Phylogeny; Pituitary cell culture; Pituitary Gland; Pituitary Gland - metabolism; Pituitary hormones; Synteny; Tissue distribution; Pituitary cell culture; Pituitary hormones; Gonadotropin subunits; NPVF; GnIH; Synteny; Phylogeny; Tissue distribution; Anguilla; GnRH-R

•A single gnih paralog has been conserved after the teleost 3R.•The gnih gene encodes three GnIH peptides in a basal teleost, the European eel.•Gnih mRNA is mostly expressed in the diencephalon in the eel.•Eel GnIH peptides inhibit the expression of lhβ, fshβ, gpα and gnrh-r2 in vitro. Since its dis...