The design and implementation of an open-source, data-driven cohort recruitment system: the Duke Integrated Subject Cohort and Enrollment Research Network (DISCERN)

• Published in: Journal of the American Medical Informatics Association : JAMIA Vol. 19; no. e1; pp. e68 - e75
• Main Authors: Ferranti, Jeffrey M, Gilbert, William, McCall, Jonathan, Shang, Howard, Barros, Tanya, Horvath, Monica M
• Format: Journal Article
• Language: English
• Published: England BMJ Group 01.06.2012
• Series: FOCUS on clinical research informatics
• Subjects: Asthma; Clinical Trials as Topic; Computer Communication Networks; Delivery of Health Care, Integrated; Health Level Seven; Humans; Internet; North Carolina; Papillomavirus Vaccines; Patient Selection; Research and Applications; North Carolina

Failure to reach research subject recruitment goals is a significant impediment to the success of many clinical trials. Implementation of health-information technology has allowed retrospective analysis of data for cohort identification and recruitment, but few institutions have also leveraged real-...