Low-level laser irradiation modulates the proliferation and the osteogenic differentiation of bone marrow mesenchymal stem cells under healthy and inflammatory condition

• Published in: Lasers in medical science Vol. 34; no. 1; pp. 169 - 178
• Main Authors: Wang, Liying, Wu, Fan, Liu, Chen, Song, Yang, Guo, Jiawen, Yang, Yanwei, Qiu, Yinong
• Format: Journal Article
• Language: English
• Published: London Springer London 01.02.2019; Springer Nature B.V
• Subjects: Alizarin; Alkaline phosphatase; Assaying; Biocompatibility; Biomedical materials; Bone marrow; Bone Marrow Cells - cytology; Cbfa-1 protein; Cell Differentiation - drug effects; Cell Differentiation - radiation effects; Cell proliferation; Cell Proliferation - drug effects; Cell Proliferation - radiation effects; Cells, Cultured; Dentistry; Differentiation (biology); Enzyme-linked immunosorbent assay; Humans; In vitro methods and tests; Inflammation; Inflammation - pathology; Interleukin-1 - metabolism; Irradiation; Lasers; Low-Level Light Therapy; Medicine; Medicine & Public Health; Mesenchymal stem cells; Mesenchymal Stem Cells - drug effects; Mesenchymal Stem Cells - metabolism; Mesenchymal Stem Cells - pathology; Mesenchymal Stem Cells - radiation effects; Mesenchyme; Microenvironments; Optical Devices; Optics; Original Article; Osteocalcin; Osteogenesis; Osteogenesis - drug effects; Osteogenesis - radiation effects; Photonics; Quantum Optics; Staining; Stem cells; Transplantation; Tumor Necrosis Factor-alpha - pharmacology; Tumor necrosis factor-TNF; Tumor necrosis factor-α; Inflammation; Proliferation; Bone marrow mesenchymal stem cells (BMSCs); Low-level laser therapy (LLLT); Osteogenesis

The aim of this in vitro study was to evaluate the effects of low-level laser therapy (LLLT) at different energy intensities on proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) under healthy and inflammatory microenvironments. Human BMSCs and BMSCs from infl...