Paraquat-induced oxidative stress regulates N6-methyladenosine (m6A) modification of circular RNAs

• Published in: Environmental pollution (1987) Vol. 290; p. 117816
• Main Authors: Chen, Nengzhou, Tang, Jianping, Su, Qianqian, Chou, Wei-Chun, Zheng, Fuli, Guo, Zhenkun, Yu, Guangxia, Shao, Wenya, Li, Huangyuan, Wu, Siying
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.12.2021
• Subjects: acetylcysteine; axons; CircRNA; gene ontology; methylation; mice; N6-methyladenosine (m6A); neurodevelopment; Neurotoxicity; Oxidative stress; Paraquat; Parkinson disease; pollution; precipitin tests; N6-methyladenosine (m6A); Oxidative stress; Paraquat; Neurotoxicity; CircRNA

Paraquat (PQ), a widely used herbicide and well-known oxidative stress inducer, has been linked to numerous neurodegenerative diseases, but the underlying mechanism(s) remains unknown. Circular RNAs (circRNAs) have recently been reported to be associated with oxidative stress in Parkinson's dis...