Spectroscopic analysis of tylosin adsorption on extracellular DNA reveals its interaction mechanism

• Published in: Colloids and surfaces, B, Biointerfaces Vol. 183; p. 110431
• Main Authors: Zhang, Qian, Peng, Qiuyan, Shu, Xiaohua, Mo, Deqing, Jiang, Dongyun
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.11.2019
• Subjects: absorption; Adsorption; agar gel electrophoresis; Animals; Antibiotic; DNA; DNA - chemistry; DNA - metabolism; electrostatic interactions; Extracellular DNA; Fluorescence; fluorescence emission spectroscopy; gene transfer; genetic variation; heavy metals; Hydrogen-Ion Concentration; Male; metal ions; Models, Molecular; Molecular Structure; Nucleic Acid Conformation; organic matter; Raman spectroscopy; Salmon; spectral analysis; Spectrum Analysis - methods; Spectrum Analysis, Raman - methods; spermatozoa; Spermatozoa - metabolism; Static Electricity; Surface enhanced Raman spectroscopy; tylosin; Tylosin - chemistry; Tylosin - metabolism; ultraviolet-visible spectroscopy; Fluorescence; Antibiotic; Adsorption; Extracellular DNA; Surface enhanced Raman spectroscopy

The diagrammatic sketch of the interaction between tylosin and DNA. [Display omitted] •The adsorption of TYL decreased with the increased concentration of DNA.•TYL may be attracted to around the DNA through electrostatic attraction.•Pyran and macrolide of TYL may intercalates into the base pair plan...