Biomaterial-assisted targeted modulation of immune cells in cancer treatment

• Published in: Nature materials Vol. 17; no. 9; pp. 761 - 772
• Main Authors: Wang, Hua, Mooney, David J.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2018; Nature Publishing Group
• Subjects: 631/250; 631/67; 639/166; 639/301; Biomaterials; Biomedical materials; Cancer; Cancer therapies; Chemistry and Materials Science; Condensed Matter Physics; Immune system; Immunotherapy; Lymphocytes; Macrophages; Maintenance; Materials Science; Modulation; Nanotechnology; Optical and Electronic Materials; Review Article; Side effects; Synergistic effect; T cell receptors

The past decade has witnessed the accelerating development of immunotherapies for cancer treatment. Immune checkpoint blockade therapies and chimeric antigen receptor (CAR)-T cell therapies have demonstrated clinical efficacy against a variety of cancers. However, issues including life-threatening o...