Assessing Genetic Influences on Behavior: Informant and Context Dependency as Illustrated by the Analysis of Attention Problems

• Published in: Behavior genetics Vol. 44; no. 4; pp. 326 - 336
• Main Authors: Kan, Kees-Jan, van Beijsterveldt, Catharina E. M., Bartels, Meike, Boomsma, Dorret I.
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.07.2014; Springer Nature B.V
• Subjects: Attention Deficit Disorder with Hyperactivity - epidemiology; Attention Deficit Disorder with Hyperactivity - genetics; Attention deficit hyperactivity disorder; Behavior; Behavioral Science and Psychology; Bias; Child; Clinical Psychology; Diseases in Twins - genetics; Faculty; Female; Genome-Wide Association Study; Health Psychology; Humans; Male; Mental disorders; Netherlands; Original Research; Parents; Psychology; Public Health; Ratings & rankings; Reproducibility of Results; Research Design; Teachers; Twins; Twins, Dizygotic - genetics; Twins, Monozygotic - genetics; Netherlands; Attention problems; (Missing) heritability; ADHD; Informant effects; Context dependent behavior
• ISSN: 0001-8244; 1573-3297; 1573-3297
• DOI: 10.1007/s10519-014-9657-7

Assessment of genetic influences on behavior depends on context, informants, and study design: We show (analytically) that, conditional on study design, informant specific genetic variance is included in the genetic variance component or in the environmental variance component. To aid the explanatio...