A closer look at the baseline-observation-carried-forward (BOCF)

• Published in: Patient preference and adherence Vol. 4; no. default; pp. 11 - 16
• Main Authors: Liu-Seifert, Hong, Zhang, Shuyu, D'Souza, Deborah, Skljarevski, Vladimir
• Format: Journal Article
• Language: English
• Published: New Zealand Taylor & Francis Ltd 01.01.2010; Dove Press; Dove Medical Press
• Subjects: discontinuation; Original Research; Pain; statistical; treatment-related; pain; statistical; discontinuation; treatment-related

The baseline-observation-carried-forward (BOCF) approach is one method to handle missing data from early treatment discontinuation. We examined modifications of this approach, taking into consideration treatment-related and nontreatment-related reasons for discontinuation. Two duloxetine chronic pai...