Resting‐state amplitude of low‐frequency fluctuation is associated with suicidal ideation

• Published in: Depression and anxiety Vol. 36; no. 5; pp. 433 - 441
• Main Authors: Lan, Martin J., Rizk, Mina M., Pantazatos, Spiro P., Rubin‐Falcone, Harry, Miller, Jeffrey M., Sublette, M. Elizabeth, Oquendo, Maria A., Keilp, John G., Mann, J. John
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01.05.2019
• Subjects: Activity patterns; Adult; biomarker; Brain mapping; Brain Mapping - methods; Caudate Nucleus - diagnostic imaging; Caudate Nucleus - physiopathology; Depressive Disorder, Major - diagnostic imaging; Depressive Disorder, Major - physiopathology; Etiology; Female; fMRI; Functional magnetic resonance imaging; Hippocampus; Hippocampus - diagnostic imaging; Hippocampus - physiopathology; Humans; Magnetic Resonance Imaging; major depressive disorder; Male; Mental depression; Mental task performance; Neuroimaging; Public health; resting state; Self destructive behavior; Suicidal Ideation; Suicide; Suicides & suicide attempts; Thalamus; Thalamus - diagnostic imaging; Thalamus - physiopathology; suicidal ideation; fMRI; resting state; major depressive disorder; biomarker; suicide

Background Identifying brain activity patterns that are associated with suicidal ideation (SI) may help to elucidate its pathogenesis and etiology. Suicide poses a significant public health problem, and SI is a risk factor for suicidal behavior. Methods Forty‐one unmedicated adult participants in a...