Characterisation, management, and outcomes of New Delhi metallo-β-lactamase-producing Escherichia coli: A case series

• Published in: Journal of Global Antimicrobial Resistance Vol. 40; pp. 42 - 46
• Main Authors: Shallal, Anita, Veve, Michael P., Kenney, Rachel M., Alangaden, George, Suleyman, Geehan
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.01.2025; Elsevier
• Subjects: Aged; Aged, 80 and over; Anti-Bacterial Agents - pharmacology; Anti-Bacterial Agents - therapeutic use; Antimicrobial resistance; Antimicrobial stewardship; beta-Lactamases - genetics; beta-Lactamases - metabolism; Carbapenemase production; Case series; Escherichia coli - drug effects; Escherichia coli - enzymology; Escherichia coli - genetics; Escherichia coli - isolation & purification; Escherichia coli Infections - drug therapy; Escherichia coli Infections - microbiology; Female; Humans; Infectious Disease; Male; Metallo-β-lactamases; Microbial Sensitivity Tests; Middle Aged; Multi-drug resistant organisms; NDM; Oral therapy; Risk Factors; Treatment Outcome; NDM; Oral therapy; Metallo-β-lactamases; Multi-drug resistant organisms; Carbapenemase production; Antimicrobial stewardship; Case series; Antimicrobial resistance

•Infections with New Delhi metallo-β-lactamase-producing Escherichia coli are difficult to treat and data are limited.•In this large case series of nine patients with culture-positive infections, two patients were re-admitted for infection-related complications within 30 days and three patients died...