Obesity, haemostasis and the fibrinolytic system

• Published in: Obesity reviews Vol. 3; no. 2; pp. 85 - 101
• Main Authors: Mertens, I., Gaal, L. F. Van
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.05.2002
• Subjects: Blood Coagulation Factors - physiology; Body Constitution - physiology; Cardiovascular Diseases - etiology; Factor VII - physiology; Factor VIII - physiology; Fibrinogen - physiology; Fibrinolysis; Fibrinolysis - physiology; haemostasis; Hemostasis - physiology; Humans; Insulin Resistance; obesity; Obesity - blood; Obesity - complications; Plasminogen Activator Inhibitor 1 - physiology; von Willebrand Factor - physiology; Weight Loss - physiology

Summary Obese patients are at risk for the development of cardiovascular diseases, which can in part be explained by disturbances in the haemostatic and fibrinolytic systems. Indeed, obese subjects tend to have higher values of fibrinogen, factor VII, factor VIII, von Willebrand factor and plasminog...