Argyrophilic Grain Disease: Demographics, Clinical, and Neuropathological Features From a Large Autopsy Study

• Published in: Journal of neuropathology and experimental neurology Vol. 75; no. 7; pp. 628 - 635
• Main Authors: Rodriguez, Roberta Diehl, Suemoto, Claudia Kimie, Molina, Mariana, Nascimento, Camila Fernandes, Leite, Renata Elaine Paraizo, de Lucena Ferretti-Rebustini, Renata Eloah, Farfel, José Marcelo, Heinsen, Helmut, Nitrini, Ricardo, Ueda, Kenji, Pasqualucci, Carlos Augusto, Jacob-Filho, Wilson, Yaffe, Kristine, Grinberg, Lea Tenenholz
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.07.2016; by American Association of Neuropathologists, Inc
• Subjects: Aged; Aged, 80 and over; Autopsy; Brazil - epidemiology; Demography - methods; Female; Humans; Male; Middle Aged; Neurodegenerative Diseases - epidemiology; Neurodegenerative Diseases - pathology; Neurodegenerative Diseases - psychology; Original; Tauopathies - epidemiology; Tauopathies - pathology; Tauopathies - psychology; Tauopathy; Neurodegeneration; Neuropathology; Postmortem; Dementia

Argyrophilic grain disease (AGD) is a frequent late-onset, 4-repeat tauopathy reported in Caucasians with high educational attainment. Little is known about AGD in non-Caucasians or in those with low educational attainment. We describe AGD demographics, clinical, and neuropathological features in a...