Japanese guidelines for the management of palmoplantar keratoderma

Palmoplantar keratoderma (PPK) is a collective term for keratinizing disorders in which the main clinical symptom is hyperkeratosis on the palms and soles. To establish the first Japanese guidelines approved by the Japanese Dermatological Association for the management of PPKs, the Committee for the...

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Published inJournal of dermatology Vol. 48; no. 8; pp. e353 - e367
Main Authors Yoneda, Kozo, Kubo, Akiharu, Nomura, Toshifumi, Ishida‐Yamamoto, Akemi, Suga, Yasushi, Akiyama, Masashi, Kanazawa, Nobuo, Hashimoto, Takashi
Format Journal Article
LanguageEnglish
Published Tokyo Wiley Subscription Services, Inc 01.08.2021
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Abstract Palmoplantar keratoderma (PPK) is a collective term for keratinizing disorders in which the main clinical symptom is hyperkeratosis on the palms and soles. To establish the first Japanese guidelines approved by the Japanese Dermatological Association for the management of PPKs, the Committee for the Management of PPKs was founded as part of the Study Group for Rare Intractable Diseases. These guidelines aim to provide current information for the management of PPKs in Japan. Based on evidence, they summarize the clinical manifestations, pathophysiologies, diagnostic criteria, disease severity determination criteria, treatment, and treatment recommendations. Because of the rarity of PPKs, there are only few clinical studies with a high degree of evidence. Therefore, several parts of these guidelines were established based on the opinions of the committee. To further optimize the guidelines, periodic revision in line with new evidence is necessary.
AbstractList Palmoplantar keratoderma (PPK) is a collective term for keratinizing disorders in which the main clinical symptom is hyperkeratosis on the palms and soles. To establish the first Japanese guidelines approved by the Japanese Dermatological Association for the management of PPKs, the Committee for the Management of PPKs was founded as part of the Study Group for Rare Intractable Diseases. These guidelines aim to provide current information for the management of PPKs in Japan. Based on evidence, they summarize the clinical manifestations, pathophysiologies, diagnostic criteria, disease severity determination criteria, treatment, and treatment recommendations. Because of the rarity of PPKs, there are only few clinical studies with a high degree of evidence. Therefore, several parts of these guidelines were established based on the opinions of the committee. To further optimize the guidelines, periodic revision in line with new evidence is necessary.
Author Kanazawa, Nobuo
Suga, Yasushi
Kubo, Akiharu
Ishida‐Yamamoto, Akemi
Nomura, Toshifumi
Akiyama, Masashi
Hashimoto, Takashi
Yoneda, Kozo
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  doi: 10.1038/ng0395-273
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  doi: 10.1016/j.ajhg.2013.09.015
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  doi: 10.1038/ng0596-70
– ident: e_1_2_2_17_35_1
  doi: 10.1007/BF01973159
– volume: 179
  start-page: 231
  year: 1989
  ident: e_1_2_2_17_10_1
  article-title: Keratosis palmoplantaris Nagashima
  publication-title: Dermatologica
  contributor:
    fullname: Mitsuhashi Y
– ident: e_1_2_2_17_44_1
  doi: 10.1136/jmg.36.12.881
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Snippet Palmoplantar keratoderma (PPK) is a collective term for keratinizing disorders in which the main clinical symptom is hyperkeratosis on the palms and soles. To...
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SubjectTerms Best practice
diagnostic algorithm
Genetic disorders
Medical diagnosis
Medical treatment
Palmoplantar keratoderma
Pathophysiology
Skin diseases
Systemic diseases
treatment
Title Japanese guidelines for the management of palmoplantar keratoderma
URI https://onlinelibrary.wiley.com/doi/abs/10.1111%2F1346-8138.15850
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Volume 48
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