Mechanisms of HBV immune evasion

• Published in: Antiviral research Vol. 179; p. 104816
• Main Authors: Kuipery, Adrian, Gehring, Adam J., Isogawa, Masanori
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2020
• Subjects: Adaptive Immunity; Animals; Exhaustion; Hepatitis B virus (HBV); Hepatitis B virus - immunology; Hepatitis B, Chronic - immunology; Humans; Immune Evasion; Immune Tolerance; Immunity, Innate; Immunosuppression; Innate immunity; Mice; Tolerance; Tolerance; Innate immunity; Immunosuppression; Adaptive immunity; Hepatitis B virus (HBV); Exhaustion

The concept of immune evasion is a longstanding topic of debate during chronic Hepatitis B Virus infection. The 292 million individuals chronically infected by HBV are clear evidence that the virus avoids elimination by the immune system. The exact mechanisms of immune evasion remain undefined and a...