Intermolecular Hydrogen Bonding in Alpha-Hydroxy Carboxylic Acids Crystals: Connectivity, Synthons, Supramolecular Motifs

• Published in: Crystals (Basel) Vol. 12; no. 10; p. 1479
• Main Authors: Bredikhin, Alexander A., Fayzullin, Robert R., Gubaidullin, Aidar T., Bredikhina, Zemfira A.
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.10.2022
• Subjects: Acids; Analysis; Carboxylic acids; chirality; Crystal structure; Crystals; Diffraction; Empirical analysis; Hydrogen; Hydrogen bonding; Hydrogen bonds; hydrogen-bonded organic frameworks; lactic acids; Organic acids; Single crystals; Structure; supramolecular interactions; synthon; X-rays; α-hydroxycarboxylic acids
• ISSN: 2073-4352; 2073-4352
• DOI: 10.3390/cryst12101479

Synthon theory underlies the analysis and empirical prediction of the crystal structure. Supramolecular synthons (SMSs) formed by intermolecular hydrogen bonds, such as carboxylic R22(8) and C11(4) and alcoholic C11(2) ones, are among the most popular. The subject of this publication is the identifi...