De novo donor-specific human leukocyte antigen antibodies early after kidney transplantation

• Published in: Transplantation Vol. 98; no. 12; p. 1310
• Main Authors: Heilman, Raymond L, Nijim, Ala, Desmarteau, Yvonne M, Khamash, Hasan, Pando, Marcelo Jorge, Smith, Maxwell L, Chakkera, Harini A, Huskey, Janna, Valdez, Riccardo, Reddy, Kunam Sudhakar
• Format: Journal Article
• Language: English
• Published: United States 27.12.2014
• Subjects: Adult; Aged; Antibodies - immunology; Biopsy; Cohort Studies; Female; Graft Rejection - immunology; Histocompatibility Antigens Class I - immunology; Histocompatibility Antigens Class II - immunology; Histocompatibility Testing; HLA Antigens - immunology; Humans; Kidney Failure, Chronic - immunology; Kidney Failure, Chronic - surgery; Kidney Transplantation; Male; Middle Aged; Retrospective Studies; Time Factors

Our aim was to determine the incidence of de novo donor-specific human leukocyte antigen (HLA) antibody (dnDSA) during the first year after kidney transplantation and the impact of early dnDSA on acute rejection and protocol biopsy findings. We selected all patients who received a kidney transplant...