Association of β-adrenergic receptor genes polymorphisms with incidence of subsequent cardiovascular events in Han Chinese patients with coronary artery disease

• Published in: Chinese medical journal Vol. 126; no. 24; pp. 4679 - 4684
• Main Authors: LI, Zhi-gen, WU, Hong, ZHOU, Ying-ling, CHEN, Zhu-jun, MENG, Jin-xiu, YANG, Jun-qing, CHEN, Ji-yan, ZHONG, Shi-long
• Format: Journal Article
• Language: English
• Published: China Department of Geriatrics, Guangzhou First People's Hospital,Guangzhou Medical University, Guangzhou, Guangdong 510045,China%Department of Cardiology, Sun Yat-sen Memorial Hospital, Sun Yatsen University, Guangzhou, Guangdong 510120, China%Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China%Medical Research Center, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, 96 Dongchuan Road, Guangzhou, Guangdong 510080,China 2013; Department of Cardiology, Guangdong Cardiovascular Institute,Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510080, China
• Subjects: Adult; Aged; Aged, 80 and over; Asian Continental Ancestry Group - genetics; Coronary Artery Disease - genetics; Female; Genotype; Humans; Incidence; Male; Middle Aged; Polymorphism, Genetic - genetics; Polymorphism, Single Nucleotide - genetics; Receptors, Adrenergic, beta - genetics; Receptors, Adrenergic, beta-1 - genetics; Receptors, Adrenergic, beta-2 - genetics; 中国汉族; 事件; 冠状动脉疾病; 发病率; 基因多态性; 心血管; 患者; 肾上腺素能受体; coronary artery disease; percutaneous coronary intervention; genetics; beta-adrenergic receptor blockers

Background Sequence variants in the 13-adrenergic receptor （ADRB） genes have a close relationship with the development of coronary artery disease （CAD） and the patient＇s prognosis. However, there is a lack of data on the role of the variants in ADRBs genes in Han Chinese patients with CAD. We aimed...