Feasibility of chitosan-alginate (Chi-Alg) hydrogel used as scaffold for neural tissue engineering: a pilot study in vitro

• Published in: Biotechnology, biotechnological equipment Vol. 31; no. 4; pp. 766 - 773
• Main Authors: Wang, Gan, Wang, Xiaoyan, Huang, Lixiang
• Format: Journal Article
• Language: English
• Published: Sofia Taylor & Francis 04.07.2017; Taylor & Francis Ltd; Taylor & Francis Group
• Subjects: alginate; Alginates; Alginic acid; Amino groups; biotechnology; cell proliferation; Chitosan; Contact angle; hydrogel; Hydrogels; hydrophilicity; Infrared spectroscopy; Ionic interactions; Natural polymers; nerve tissue; Nervous tissues; Neural stem cells; Olfactory ensheathing cells; Polymers; Scaffolding; Scanning electron microscopy; Stem cells; Tissue engineering; X-ray diffraction

In tissue engineering, scaffolding plays an important role in accommodating and stimulating new tissue growth. Chitosan and alginate are two widely used natural polymers in tissue engineering. Here, we prepared the chitosan-alginate (Chi-Alg) hydrogel from naturally derived chitosan and alginate pol...