Advanced and Biomedical Applications of Schiff-Base Ligands and Their Metal Complexes: A Review

Because of their importance in a variety of interdisciplinary study domains, Schiff-base ligands have performed a significant role in the evolution of contemporary coordination chemistry. This almost-comprehensive review covers all the aspects and properties of complexes, starting from the Schiff-ba...

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Published inCrystals (Basel) Vol. 12; no. 10; p. 1436
Main Authors Soroceanu, Alina, Bargan, Alexandra
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.10.2022
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Abstract Because of their importance in a variety of interdisciplinary study domains, Schiff-base ligands have performed a significant role in the evolution of contemporary coordination chemistry. This almost-comprehensive review covers all the aspects and properties of complexes, starting from the Schiff-base ligands. Our work is centered on the eloquent advances that have been developed since 2015, with special consideration to recent developments. Schiff-base ligands and their complexes are adaptable compounds obtained from the condensation of two compounds: a carbonyl with an amino. The correspondent metal complexes have been shown to have antifungal, antibacterial, antioxidant, antiproliferative, and antiviral properties. This review begins with a short introduction to Schiff-base ligands and their metal complexes. It stands out in the recent advancements in the Schiff-base coordination chemistry domain and its future prospects as a potential bioactive core. Additionally, the review contains knowledge about the antioxidant, redox, and catalytic activities of the Schiff-base complexes, with important future applications in the obtaining of new compounds and materials.
AbstractList Because of their importance in a variety of interdisciplinary study domains, Schiff-base ligands have performed a significant role in the evolution of contemporary coordination chemistry. This almost-comprehensive review covers all the aspects and properties of complexes, starting from the Schiff-base ligands. Our work is centered on the eloquent advances that have been developed since 2015, with special consideration to recent developments. Schiff-base ligands and their complexes are adaptable compounds obtained from the condensation of two compounds: a carbonyl with an amino. The correspondent metal complexes have been shown to have antifungal, antibacterial, antioxidant, antiproliferative, and antiviral properties. This review begins with a short introduction to Schiff-base ligands and their metal complexes. It stands out in the recent advancements in the Schiff-base coordination chemistry domain and its future prospects as a potential bioactive core. Additionally, the review contains knowledge about the antioxidant, redox, and catalytic activities of the Schiff-base complexes, with important future applications in the obtaining of new compounds and materials.
Audience Academic
Author Soroceanu, Alina
Bargan, Alexandra
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Snippet Because of their importance in a variety of interdisciplinary study domains, Schiff-base ligands have performed a significant role in the evolution of...
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SubjectTerms Amino acids
antimicrobial activity
Antimicrobial agents
antioxidant activity
Antioxidants
Biochemistry
Biological activity
Biomedical materials
Carbonyls
Catalysis
catalytic activity
Coordination compounds
Copper
Domains
Fungicides
Gram-positive bacteria
Health aspects
Imines
Interdisciplinary studies
Investigations
Ligands
Materials science
Nitrogen
redox activity
Schiff bases
Schiff-base complexes
siloxane
Single crystals
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Title Advanced and Biomedical Applications of Schiff-Base Ligands and Their Metal Complexes: A Review
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