Model discovery approach enables noninvasive measurement of intra-tumoral fluid transport in dynamic MRI

• Published in: APL bioengineering Vol. 8; no. 2; p. 026106
• Main Authors: Woodall, Ryan T., Esparza, Cora C., Gutova, Margarita, Wang, Maosen, Cunningham, Jessica J., Brummer, Alexander B., Stine, Caleb A., Brown, Christine C., Munson, Jennifer M., Rockne, Russell C.
• Format: Journal Article
• Language: English
• Published: United States AIP Publishing LLC 01.06.2024

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a routine method to noninvasively quantify perfusion dynamics in tissues. The standard practice for analyzing DCE-MRI data is to fit an ordinary differential equation to each voxel. Recent advances in data science provide an opportuni...