Association of environmental benzo[a]pyrene exposure and DNA methylation alterations in hepatocellular carcinoma: A Chinese case–control study - Tian, Meiping; Zhao, Benhua; Zhang, Jie; Martin, Francis L.; Huang, Qingyu; Liu, Liangpo; Shen, Heqing (The Science of the total environment, 2016)
Keywords: Adult; alcohol drinking; Alterations; B[a]P; benzo(a)pyrene; Benzo(a)pyrene - toxicity; blood sampling; blood serum; Carcinoma, Hepatocellular - epidemiology; Carcinoma, Hepatocellular - metabolism; Case control study; Case-Control Studies; China; China - epidemiology; correlation; cytotoxicity; Deoxyribonucleic acid; DNA Methylation; Ecological risk assessment; Environmental Exposure - statistics & numerical data; environmental factors; Environmental Pollutants - toxicity; Epidemiology; Epigenetic; epigenetics; Female; Genes; glutathione transferase; GSTP; hepatitis B; Hepatitis B virus; Hepatitis C virus; Hepatocellular carcinoma; hepatocytes; hepatoma; Humans; Liver Neoplasms - epidemiology; Liver Neoplasms - metabolism; Male; Mathematical models; melting; Methylation; Middle Aged; patients; promoter regions; protective effect; Risk analysis; risk factors; tumor suppressor genes; viruses; volunteers; China; China, People's Rep; DNA methylation; GSTP; Hepatocellular carcinoma; Case control study; Epigenetic; B[a]P