Circulating proteasomes after burn injury

• Published in: Journal of burn care & research Vol. 31; no. 2; p. 243
• Main Authors: Majetschak, Matthias, Zedler, Siegfried, Romero, Jacqueline, Albright, Joslyn M, Kraft, Robert, Kovacs, Elizabeth J, Faist, Eugen, Gamelli, Richard L
• Format: Journal Article
• Language: English
• Published: England 01.03.2010
• Subjects: Adult; Burns - enzymology; Case-Control Studies; Enzyme-Linked Immunosorbent Assay; Female; Humans; Injury Severity Score; Male; Multiple Organ Failure - enzymology; Oligopeptides; Proteasome Endopeptidase Complex - blood; Regression Analysis; ROC Curve; Sensitivity and Specificity; Sepsis - enzymology; Smoke Inhalation Injury - enzymology; Statistics, Nonparametric

The objective of the study is to test whether circulating proteasomes are increased in burn patients and to assess whether possible alterations are associated with severity of injury, organ failure, and/or clinically relevant outcomes. In this study, plasma was obtained from burn patients on days 0...