The Oncogene Nup98-HOXA9 Induces Gene Transcription in Myeloid Cells
The nucleoporin Nup98 gene is frequently rearranged in acute myelogenous leukemia (AML). In most cases this results in fusion of the N terminus of Nup98 to the DNA binding domain of a homeodomain transcription factor. The prototype of these fusions, Nup98-HOXA9, is associated with human AML and indu...
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Published in | The Journal of biological chemistry Vol. 279; no. 2; pp. 866 - 875 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
09.01.2004
American Society for Biochemistry and Molecular Biology |
Subjects | |
Online Access | Get full text |
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