Neoadjuvant therapy for resectable pancreatic cancer

• Published in: World journal of gastrointestinal oncology Vol. 9; no. 12; pp. 457 - 465
• Main Authors: Rahman, Sheikh Hasibur, Urquhart, Robin, Molinari, Michele
• Format: Journal Article
• Language: English
• Published: China Baishideng Publishing Group Inc 15.12.2017
• Subjects: Minireviews; Neoadjuvant chemotherapy; Phase III trial; Borderline resectable; Phase II trial; Pancreatic adenocarcinoma; Phase I trial; Neoadjuvant chemoradiation therapy; Decision analysis; Randomized controlled trial; Locally advanced; Meta-analysis

The use of neoadjuvant therapies has played a major role for borderline resectable and locally advanced pancreatic cancers(PCs). For this group of patients, preoperative chemotherapy or chemoradiation has increased the likelihood of surgery with negative resection margins and overall survival. On th...