Highly sensitive nano-porous lattice biosensor based on localized surface plasmon resonance and interference

• Published in: Optics express Vol. 19; no. 23; pp. 22882 - 22891
• Main Authors: Yeom, Se-Hyuk, Kim, Ok-Geun, Kang, Byoung-Ho, Kim, Kyu-Jin, Yuan, Heng, Kwon, Dae-Hyuk, Kim, Hak-Rin, Kang, Shin-Won
• Format: Journal Article
• Language: English
• Published: United States 07.11.2011
• Subjects: Aluminum Oxide - chemistry; Antibodies, Immobilized; Antigens - analysis; Antigens - immunology; C-Reactive Protein - analysis; C-Reactive Protein - immunology; Electrodes; Gold - chemistry; Humans; Membranes, Artificial; Microscopy, Atomic Force; Nanostructures - chemistry; Nanostructures - ultrastructure; Porosity; Surface Plasmon Resonance - methods

We propose a design for a highly sensitive biosensor based on nanostructured anodized aluminum oxide (AAO) substrates. A gold-deposited AAO substrate exhibits both optical interference and localized surface plasmon resonance (LSPR). In our sensor, application of these disparate optical properties ov...