Association between ATG16L1 rs2241880(T300A) and rs4663421 and ANCA‑associated vasculitis in the Guangxi population of China: Propensity score matching analysis

• Published in: Biomedical reports Vol. 22; no. 1; p. 3
• Main Authors: Tang, Wenlv, Zhang, Yurong, Lu, Shurong, Xue, Chao
• Format: Journal Article
• Language: English
• Published: England Spandidos Publications 01.01.2025; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Age; Age composition; Analysis; Annealing; Antineutrophil cytoplasmic antibodies; Autoimmune diseases; Autophagy; Blood; C-reactive protein; Disease; Disease susceptibility; Ethylenediaminetetraacetic acid; Frequency distribution; Gene frequency; Gene polymorphism; Genes; Genetic analysis; Genetic aspects; Hospitals; Linkage analysis; Linkage disequilibrium; Matching; Metabolism; Microorganisms; Neutrophils; Nucleotides; Pathogenesis; Polymorphism; Proteins; Sclerosis; Single nucleotide polymorphisms; Single-nucleotide polymorphism; Software; Statistical analysis; Tumors; Vasculitis; China; Beijing China; gene polymorphism; propensity score matching; autophagy gene; ANCA-associated vasculitis

Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a rare autoimmune disease with an unclear pathogenesis. The present study investigated the associations between autophagy-related protein 16-like 1 (ATG16L1) rs2241880(T300A) and rs4663421 and AAV. A total of 177 patients with AAV an...