Neutropenic Enterocolitis in a Child with Acute Myeloid Leukemia Successfully Treated with Early Surgical Intervention

Neutropenic entrocolitis (NE) is a life threatening complication of acute leukemia. The case presented here is of a 12 year old boy with acute myeloid leukemia, who developed neutropenic enterocolitis after induction with BFM-93 protocol. Patient underwent exploratory laparotomy during grade 4 neutr...

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Published inIndian journal of hematology & blood transfusion Vol. 29; no. 3; pp. 181 - 183
Main Authors Lingutla, Arun Kumar, Anand, Asha S., Shah, Sandip A., Patel, Apurva A., Kumar, Sumit, Shah, Pankaj M., Shukla, Shilin N., Parikh, Bharat J., Talati, Shailesh S., Panchal, Harsha, Parikh, Sonia, Parekh, Bhavesh B., Bhatt, Shivani J.
Format Journal Article
LanguageEnglish
Published India Springer India 01.09.2013
Springer Nature B.V
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Abstract Neutropenic entrocolitis (NE) is a life threatening complication of acute leukemia. The case presented here is of a 12 year old boy with acute myeloid leukemia, who developed neutropenic enterocolitis after induction with BFM-93 protocol. Patient underwent exploratory laparotomy during grade 4 neutropenia after failure on conservative line of management of NE. Patient withstood the procedure with supportive care and recovered. This case is reported because NE is a rare but potentially fatal complication and there are no clear guidelines for surgical intervention.
AbstractList Neutropenic entrocolitis (NE) is a life threatening complication of acute leukemia. The case presented here is of a 12 year old boy with acute myeloid leukemia, who developed neutropenic enterocolitis after induction with BFM-93 protocol. Patient underwent exploratory laparotomy during grade 4 neutropenia after failure on conservative line of management of NE. Patient withstood the procedure with supportive care and recovered. This case is reported because NE is a rare but potentially fatal complication and there are no clear guidelines for surgical intervention.
Neutropenic entrocolitis (NE) is a life threatening complication of acute leukemia. The case presented here is of a 12 year old boy with acute myeloid leukemia, who developed neutropenic enterocolitis after induction with BFM-93 protocol. Patient underwent exploratory laparotomy during grade 4 neutropenia after failure on conservative line of management of NE. Patient withstood the procedure with supportive care and recovered. This case is reported because NE is a rare but potentially fatal complication and there are no clear guidelines for surgical intervention.
Author Parikh, Bharat J.
Shah, Sandip A.
Kumar, Sumit
Shukla, Shilin N.
Panchal, Harsha
Anand, Asha S.
Patel, Apurva A.
Bhatt, Shivani J.
Shah, Pankaj M.
Parikh, Sonia
Parekh, Bhavesh B.
Lingutla, Arun Kumar
Talati, Shailesh S.
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  givenname: Bharat J.
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  givenname: Bhavesh B.
  surname: Parekh
  fullname: Parekh, Bhavesh B.
  organization: Department of Medical Oncology and Paediatric Surgery, The Gujarat Cancer & Research Institute
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  givenname: Shivani J.
  surname: Bhatt
  fullname: Bhatt, Shivani J.
  organization: Department of Medical Oncology and Paediatric Surgery, The Gujarat Cancer & Research Institute
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10.1055/s-2001-16849
10.1093/clinids/17.3.484
10.4103/0019-509X.38946
10.1007/s00247-005-0014-0
10.1002/cncr.21134
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Acute Myeloid Leukemia
Bowel Wall Thickness
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Snippet Neutropenic entrocolitis (NE) is a life threatening complication of acute leukemia. The case presented here is of a 12 year old boy with acute myeloid...
Neutropenic entrocolitis (NE) is a life threatening complication of acute leukemia. The case presented here is of a 12 year old boy with acute myeloid...
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SubjectTerms Blood Transfusion Medicine
Case Report
Gastrointestinal diseases
Gastrointestinal surgery
Hematology
Human Genetics
Leukemia
Medicine
Medicine & Public Health
Oncology
Pediatrics
Surgical outcomes
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Title Neutropenic Enterocolitis in a Child with Acute Myeloid Leukemia Successfully Treated with Early Surgical Intervention
URI https://link.springer.com/article/10.1007/s12288-012-0176-5
https://www.ncbi.nlm.nih.gov/pubmed/24426370
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https://pubmed.ncbi.nlm.nih.gov/PMC3710551
Volume 29
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