Novel esophageal squamous cell carcinoma bone metastatic clone isolated by scintigraphy, X ray and micro PET/CT

• Published in: World journal of gastroenterology : WJG Vol. 20; no. 4; pp. 1030 - 1037
• Main Author: Zhao, Bi-Zeng
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Co., Limited 28.01.2014
• Subjects: Animals; Bone; Bone Neoplasms - diagnostic imaging; Bone Neoplasms - genetics; Bone Neoplasms - secondary; carcinoma; Carcinoma, Squamous Cell - diagnostic imaging; Carcinoma, Squamous Cell - genetics; Carcinoma, Squamous Cell - secondary; Carcinoma, Squamous Cell - surgery; cell; Cell Line, Tumor; Chromosomes, Human; Esophageal; Esophageal Neoplasms - genetics; Esophageal Neoplasms - pathology; Esophageal Neoplasms - surgery; Esophageal Squamous Cell Carcinoma; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Karyotyping; line; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Multimodal Imaging - methods; Neoplasm Transplantation; Original; Positron-Emission Tomography; Predictive Value of Tests; Radiopharmaceuticals; squamous; Technetium Tc 99m Medronate; X-Ray Microtomography; Molecular imaging; Esophageal squamous cell carcinoma; Bone metastasis; Cell line; Real-time polymerase chain reaction

AIM:To establish a Chinese esophageal squamous cell carcinoma(ESCC)cell line with high bone metastasis potency using99mTc-methylene diphosphonate(99mTcMDP)micro-pinhole scintigraphy,X ray and micropositron emission tomography/computed tomography(PET/CT)for exploring the mechanism of occurrence and d...