Role of pentoxifylline in non-alcoholic fatty liver disease in high-fat diet-induced obesity in mice

• Published in: World journal of hepatology Vol. 7; no. 24; pp. 2551 - 2558
• Main Authors: Acedo, Simone Coghetto, Caria, Cintia Rabelo E Paiva, Gotardo, Érica Martins Ferreira, Pereira, José Aires, Pedrazzoli, José, Ribeiro, Marcelo Lima, Gambero, Alessandra
• Format: Journal Article
• Language: English
• Published: United States Baishideng Publishing Group Inc 28.10.2015
• Subjects: Basic Study; Pentoxifylline;Steatosis;Obesity;Adipose; tissue;Ad; Pentoxifylline; Obesity; Adipose tissue; Adipokine; Tumor necrosis factor-α; Steatosis

AIM:To study pentoxifylline effects in liver and adipose tissue inflammation in obese mice induced by high-fat diet(HFD).METHODS: Male swiss mice(6-wk old) were fed a highfat diet(HFD; 60% kcal from fat) or AIN-93(control diet; 15% kcal from fat) for 12 wk and received pentoxifylline intraperitoneal...