Presence of hemoglobinopathies in Sicily: a historic perspective

• Published in: American journal of medical genetics Vol. 69; no. 2; p. 200
• Main Authors: Schilirò, G, Mirabile, E, Testa, R, Russo-Mancuso, G, Dibenedetto, S P
• Format: Journal Article
• Language: English
• Published: United States 17.03.1997
• Subjects: Adolescent; Adult; Aged; Alleles; alpha-Thalassemia - epidemiology; alpha-Thalassemia - genetics; beta-Thalassemia - epidemiology; beta-Thalassemia - genetics; Child; Child, Preschool; Female; Globins - genetics; Hemoglobins, Abnormal - genetics; Heterozygote; Humans; Infant; Male; Middle Aged; Point Mutation; Sicily - epidemiology; Sicily

Sicily, at the center of the Mediterranean, has been the meeting place of Eastern and Western civilizations, and in the Sicilian population the presence of many different alterations in the globin gene clusters can surely be considered testimony of past colonizations. From 1975 to 1994, 100,000 Sici...