Vortex duration in the pulmonary artery does not depend on vascular Afterload: a sign of adaptation?

• Published in: COMPUTERS IN BIOLOGY AND MEDICINE Vol. 196; no. Pt A; p. 110717
• Main Authors: Sabry, Malak, Wieslander, Björn, Hermida, Uxio, Fernandes, Joao Filipe, Keramati, Hamed, Ugander, Martin, Abdula, Goran, Yacoub, Magdi H., Lamata, Pablo, Marlevi, David, De Vecchi, Adelaide
• Format: Journal Article Publication
• Language: English
• Published: United States Elsevier Ltd 01.09.2025
• Subjects: 4D flow MRI; Adult; CFD; Computer Simulation; Digital twins; Female; Humans; Hypertension, Pulmonary - diagnostic imaging; Hypertension, Pulmonary - physiopathology; Internal Medicine; Magnetic Resonance Imaging; Male; Middle Aged; Models, Cardiovascular; Other; Pulmonary Artery - diagnostic imaging; Pulmonary Artery - physiopathology; Pulmonary hypertension; Vorticity; CFD; 4D flow MRI; Digital twins; Pulmonary hypertension; Vorticity

Pulmonary Hypertension (PH) is a serious condition defined by a mean Pulmonary Arterial Pressure (mPAP) greater than 20 mmHg. Using 4D Flow MRI, a strong empirical correlation has been observed between the duration of a blood vortex in the Main Pulmonary Artery (MPA) and mPAP. The mechanisms underly...