Cerebral metabolic pattern in young adult Down's syndrome subjects: altered intercorrelations between regional rates of glucose utilization

• Published in: Journal of mental deficiency research Vol. 34 ( Pt 3); p. 237
• Main Authors: Horwitz, B, Schapiro, M B, Grady, C L, Rapoport, S I
• Format: Journal Article
• Language: English
• Published: England 01.06.1990
• Subjects: Adult; Blood Glucose - metabolism; Brain - diagnostic imaging; Brain Mapping; Cerebral Cortex - diagnostic imaging; Deoxyglucose - analogs & derivatives; Deoxyglucose - metabolism; Dominance, Cerebral - physiology; Down Syndrome - diagnostic imaging; Female; Fluorodeoxyglucose F18; Humans; Male; Tomography, Emission-Computed

Correlations between regional cerebral metabolic rates for glucose, determined by positron emission tomography with [18F]-2-fluoro-2-deoxy-D-glucose, have been used to indicate functional associations between pairs of brain regions. This method was applied to data from 14 healthy adult subjects with...