Inhaled Adrenaline in Acute Bronchiolitis
To the Editor: Skjerven and colleagues (June 13 issue) 1 reported that inhaled racemic adrenaline is not more effective than inhaled saline in infants with acute bronchiolitis. Inhaled therapies are used frequently to treat children with bronchiolitis, 2 despite the lack of evidence from clinical tr...
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| Published in | The New England journal of medicine Vol. 369; no. 11; pp. 1075 - 1077 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Massachusetts Medical Society
12.09.2013
|
| Subjects | |
| Online Access | Get full text |
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| Abstract | To the Editor:
Skjerven and colleagues (June 13 issue)
1
reported that inhaled racemic adrenaline is not more effective than inhaled saline in infants with acute bronchiolitis. Inhaled therapies are used frequently to treat children with bronchiolitis,
2
despite the lack of evidence from clinical trials and recommendations against their use.
3
The American Academy of Pediatrics recommendations for bronchiolitis state, “A carefully monitored trial of α-adrenergic or β-adrenergic medication is an option. Inhaled bronchodilators should be continued only if there is a documented positive clinical response to the trial using an objective means of evaluation.”
3
We wonder whether the authors could identify . . . |
|---|---|
| AbstractList | To the Editor:
Skjerven and colleagues (June 13 issue)
1
reported that inhaled racemic adrenaline is not more effective than inhaled saline in infants with acute bronchiolitis. Inhaled therapies are used frequently to treat children with bronchiolitis,
2
despite the lack of evidence from clinical trials and recommendations against their use.
3
The American Academy of Pediatrics recommendations for bronchiolitis state, “A carefully monitored trial of α-adrenergic or β-adrenergic medication is an option. Inhaled bronchodilators should be continued only if there is a documented positive clinical response to the trial using an objective means of evaluation.”
3
We wonder whether the authors could identify . . . To the Editor: Skjerven and colleagues (June 13 issue)1 reported that inhaled racemic adrenaline is not more effective than inhaled saline in infants with acute bronchiolitis. Inhaled therapies are used frequently to treat children with bronchiolitis,2 despite the lack of evidence from clinical trials and recommendations against their use.3 The American Academy of Pediatrics recommendations for bronchiolitis state, “A carefully monitored trial of α-adrenergic or β-adrenergic medication is an option. Inhaled bronchodilators should be continued only if there is a documented positive clinical response to the trial using an objective means of evaluation.”3 We wonder whether the authors could identify . . . |
| Author | Ruiz-Contreras, Jesús Skjerven, Håvard Ove Carlsen, Kai-Håkon Garcia, Pedro Celiny R Branco, Ricardo G Carlsen, Karin C. Lødrup Gonzalez-Granado, Luis Ignacio Tasker, Robert C |
| Author_xml | – sequence: 1 givenname: Ricardo G surname: Branco fullname: Branco, Ricardo G email: rgb35@medschl.cam.ac.uk organization: Addenbrooke's Hospital, Cambridge, United Kingdom – sequence: 2 givenname: Pedro Celiny R surname: Garcia fullname: Garcia, Pedro Celiny R organization: Hospital São Lucas da PUCRS, Porto Alegre, Brazil – sequence: 3 givenname: Robert C surname: Tasker fullname: Tasker, Robert C organization: Harvard Medical School, Boston, MA – sequence: 4 givenname: Jesús surname: Ruiz-Contreras fullname: Ruiz-Contreras, Jesús email: jruizcontreras@gmail.com organization: Hospital 12 Octubre, Madrid, Spain – sequence: 5 givenname: Luis Ignacio surname: Gonzalez-Granado fullname: Gonzalez-Granado, Luis Ignacio email: jruizcontreras@gmail.com organization: Hospital 12 Octubre, Madrid, Spain – sequence: 6 givenname: Håvard Ove surname: Skjerven fullname: Skjerven, Håvard Ove email: h.o.skjerven@medisin.uio.no organization: Oslo University Hospital, Oslo, Norway – sequence: 7 givenname: Kai-Håkon surname: Carlsen fullname: Carlsen, Kai-Håkon email: h.o.skjerven@medisin.uio.no organization: Oslo University Hospital, Oslo, Norway – sequence: 8 givenname: Karin C. Lødrup surname: Carlsen fullname: Carlsen, Karin C. Lødrup email: h.o.skjerven@medisin.uio.no organization: Oslo University Hospital, Oslo, Norway |
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| Snippet | To the Editor:
Skjerven and colleagues (June 13 issue)
1
reported that inhaled racemic adrenaline is not more effective than inhaled saline in infants with... To the Editor: Skjerven and colleagues (June 13 issue)1 reported that inhaled racemic adrenaline is not more effective than inhaled saline in infants with... |
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| SubjectTerms | Bronchiolitis - drug therapy Bronchodilators Bronchopneumonia Children Clinical trials Epinephrine Epinephrine - administration & dosage Female Humans Infants Male Respiratory therapy Sodium Chloride - administration & dosage |
| Title | Inhaled Adrenaline in Acute Bronchiolitis |
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