Inhaled Adrenaline in Acute Bronchiolitis

To the Editor: Skjerven and colleagues (June 13 issue) 1 reported that inhaled racemic adrenaline is not more effective than inhaled saline in infants with acute bronchiolitis. Inhaled therapies are used frequently to treat children with bronchiolitis, 2 despite the lack of evidence from clinical tr...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 369; no. 11; pp. 1075 - 1077
Main Authors Branco, Ricardo G, Garcia, Pedro Celiny R, Tasker, Robert C, Ruiz-Contreras, Jesús, Gonzalez-Granado, Luis Ignacio, Skjerven, Håvard Ove, Carlsen, Kai-Håkon, Carlsen, Karin C. Lødrup
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 12.09.2013
Subjects
Bronchiolitis - drug therapy
Bronchodilators
Bronchopneumonia
Children
Clinical trials
Epinephrine
Epinephrine - administration & dosage
Female
Humans
Infants
Male
Respiratory therapy
Sodium Chloride - administration & dosage
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Summary:To the Editor: Skjerven and colleagues (June 13 issue) 1 reported that inhaled racemic adrenaline is not more effective than inhaled saline in infants with acute bronchiolitis. Inhaled therapies are used frequently to treat children with bronchiolitis, 2 despite the lack of evidence from clinical trials and recommendations against their use. 3 The American Academy of Pediatrics recommendations for bronchiolitis state, “A carefully monitored trial of α-adrenergic or β-adrenergic medication is an option. Inhaled bronchodilators should be continued only if there is a documented positive clinical response to the trial using an objective means of evaluation.” 3 We wonder whether the authors could identify . . .
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc1308964