Once is not enough: withholding postoperative prophylactic antibiotics in prosthetic breast reconstruction is associated with an increased risk of infection

• Published in: Plastic and reconstructive surgery (1963) Vol. 130; no. 3; p. 495
• Main Authors: Clayton, John L, Bazakas, Andrea, Lee, Clara N, Hultman, C Scott, Halvorson, Eric G
• Format: Journal Article
• Language: English
• Published: United States 01.09.2012
• Subjects: Administration, Oral; Anti-Bacterial Agents - administration & dosage; Antibiotic Prophylaxis; Breast Implantation - adverse effects; Breast Implantation - methods; Breast Neoplasms - epidemiology; Breast Neoplasms - surgery; Comorbidity; Diabetes Mellitus - epidemiology; Drug Administration Schedule; Female; Humans; Incidence; Infusions, Intravenous; Mastectomy; Middle Aged; Multivariate Analysis; Reconstructive Surgical Procedures - adverse effects; Reoperation; Retrospective Studies; Risk Factors; Smoking - epidemiology; Surgical Wound Infection - epidemiology; Surgical Wound Infection - etiology; Surgical Wound Infection - prevention & control; Surgical Wound Infection - surgery; Withholding Treatment

There has been a trend toward limiting perioperative prophylactic antibiotics, based on research not conducted in plastic surgery patients. The authors' university hospital instituted antibiotic prescribing guidelines based on the Surgical Care Improvement Project. An increased rate of surgical...