Limited utility of novel serological biomarkers in patients newly suspected of having giant cell arteritis

• Published in: International journal of rheumatic diseases Vol. 24; no. 6; pp. 781 - 788
• Main Authors: Sammel, Anthony M., Xue, Meilang, Karsten, Elisabeth, Little, Christopher B., Smith, Susan, Nguyen, Katherine, Laurent, Rodger
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.06.2021
• Subjects: Arteritis; Biomarkers; Biopsy; Computed tomography; Corticosteroids; Diagnosis; enzyme‐linked immunosorbent assay; Erythrocyte sedimentation rate; giant cell arteritis; immunoassay; Interferon; Interleukin 1; Interleukin 12; interleukin‐6; Pentraxins; Positron emission tomography; Procalcitonin; Serology; Vascular endothelial growth factor; Vasculitis; Von Willebrand factor; giant cell arteritis; vasculitis; interleukin-6; enzyme-linked immunosorbent assay; immunoassay

Aim Diagnosing and monitoring vascular activity in giant cell arteritis (GCA) is difficult due to the paucity of specific serological biomarkers. We assessed the utility of 8 novel biomarkers in an inception cohort of newly suspected GCA patients. Method Consecutive patients were enrolled between Ma...