Chiral phosphoric acid-catalyzed asymmetric dearomatization reactions

• Published in: Chemical Society reviews Vol. 49; no. 1; pp. 286 - 3
• Main Authors: Xia, Zi-Lei, Xu-Xu, Qing-Feng, Zheng, Chao, You, Shu-Li
• Format: Journal Article
• Language: English
• Published: England Royal Society of Chemistry 02.01.2020
• Subjects: Aromatic compounds; aromatic hydrocarbons; Asymmetry; benzofurans; catalysts; Chemical reactions; Indoles; isoquinolines; Lewis acids; Lewis bases; naphthols; Nucleophiles; Organic compounds; Phenols; Phosphoric acid; Pyridines; quinolines

We summarize in this review the recent development of chiral phosphoric acid (CPA)-catalyzed asymmetric dearomatization reactions. A wide array of electron-rich arenes (indoles, phenols, naphthols, benzothiophenes, benzofurans, etc. ) and electron-poor arenes (pyridines, quinolines, isoquinolines, e...