Impact of Clinical, Laboratory and Fluid Therapy Variables on Hospital Length of Stay for Children with Acute Pancreatitis
There have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed consensus guidelines on management but it is unclear if these are sufficient or valid. Our study aims to assess the effect of clinical and laboratory...
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Published in | Pediatric gastroenterology, hepatology & nutrition Vol. 23; no. 4; pp. 356 - 365 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Korea (South)
The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
01.07.2020
대한소아소화기영양학회 |
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Abstract | There have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed consensus guidelines on management but it is unclear if these are sufficient or valid. Our study aims to assess the effect of clinical and laboratory variables, in addition to treatment modality on hospital length of stay (LOS) as a proxy variable for severity in pediatric patients admitted with AP.
We conducted a retrospective chart review of patients between ages of 0-18 years, who were admitted with AP at 2 institutions between 2013-2018, John R. Oishei Children's Hospital (Buffalo, NY, USA) and Medical University of South Carolina Children's Hospital (Charleston, SC, USA). We constructed three linear regression models to analyze the effect of clinical signs of organ dysfunction, laboratory markers and fluid intake on hospital LOS.
Ninety-two patients were included in the study. The mean age was 12 years (range, 7.6-17.4 years), 55% were females, and median LOS was 3 days. The most frequent cause of AP was idiopathic. Our study showed that elevated blood urea nitrogen (BUN) on admission (
<0.005), tachycardia that lasted for ≥48 hours (
<0.001) and need for fluid resuscitation were associated with increase LOS. Total daily fluid intake above maintenance did not have a significant effect on the primary outcome (
=0.49).
Elevated serum BUN on admission, persistent tachycardia and need for fluid resuscitation were associated with increase LOS in pediatric AP. Daily total fluid intake above recommended maintenance did not reduce LOS. |
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AbstractList | Purpose: There have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed consensus guidelines on management but it is unclear if these are sufficient or valid. Our study aims to assess the effect of clinical and laboratory variables, in addition to treatment modality on hospital length of stay (LOS) as a proxy variable for severity in pediatric patients admitted with AP.
Methods: We conducted a retrospective chart review of patients between ages of 0–18 years, who were admitted with AP at 2 institutions between 2013–2018, John R. Oishei Children's Hospital (Buffalo, NY, USA) and Medical University of South Carolina Children's Hospital (Charleston, SC, USA). We constructed three linear regression models to analyze the effect of clinical signs of organ dysfunction, laboratory markers and fluid intake on hospital LOS.
Results: Ninety-two patients were included in the study. The mean age was 12 years (range, 7.6–17.4 years), 55% were females, and median LOS was 3 days. The most frequent cause of AP was idiopathic. Our study showed that elevated blood urea nitrogen (BUN) on admission (p<0.005), tachycardia that lasted for ≥48 hours (p<0.001) and need for fluid resuscitation were associated with increase LOS. Total daily fluid intake above maintenance did not have a significant effect on the primary outcome (p=0.49).
Conclusion: Elevated serum BUN on admission, persistent tachycardia and need for fluid resuscitation were associated with increase LOS in pediatric AP. Daily total fluid intake above recommended maintenance did not reduce LOS. KCI Citation Count: 0 There have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed consensus guidelines on management but it is unclear if these are sufficient or valid. Our study aims to assess the effect of clinical and laboratory variables, in addition to treatment modality on hospital length of stay (LOS) as a proxy variable for severity in pediatric patients admitted with AP. We conducted a retrospective chart review of patients between ages of 0-18 years, who were admitted with AP at 2 institutions between 2013-2018, John R. Oishei Children's Hospital (Buffalo, NY, USA) and Medical University of South Carolina Children's Hospital (Charleston, SC, USA). We constructed three linear regression models to analyze the effect of clinical signs of organ dysfunction, laboratory markers and fluid intake on hospital LOS. Ninety-two patients were included in the study. The mean age was 12 years (range, 7.6-17.4 years), 55% were females, and median LOS was 3 days. The most frequent cause of AP was idiopathic. Our study showed that elevated blood urea nitrogen (BUN) on admission ( <0.005), tachycardia that lasted for ≥48 hours ( <0.001) and need for fluid resuscitation were associated with increase LOS. Total daily fluid intake above maintenance did not have a significant effect on the primary outcome ( =0.49). Elevated serum BUN on admission, persistent tachycardia and need for fluid resuscitation were associated with increase LOS in pediatric AP. Daily total fluid intake above recommended maintenance did not reduce LOS. PURPOSEThere have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed consensus guidelines on management but it is unclear if these are sufficient or valid. Our study aims to assess the effect of clinical and laboratory variables, in addition to treatment modality on hospital length of stay (LOS) as a proxy variable for severity in pediatric patients admitted with AP. METHODSWe conducted a retrospective chart review of patients between ages of 0-18 years, who were admitted with AP at 2 institutions between 2013-2018, John R. Oishei Children's Hospital (Buffalo, NY, USA) and Medical University of South Carolina Children's Hospital (Charleston, SC, USA). We constructed three linear regression models to analyze the effect of clinical signs of organ dysfunction, laboratory markers and fluid intake on hospital LOS. RESULTSNinety-two patients were included in the study. The mean age was 12 years (range, 7.6-17.4 years), 55% were females, and median LOS was 3 days. The most frequent cause of AP was idiopathic. Our study showed that elevated blood urea nitrogen (BUN) on admission (p<0.005), tachycardia that lasted for ≥48 hours (p<0.001) and need for fluid resuscitation were associated with increase LOS. Total daily fluid intake above maintenance did not have a significant effect on the primary outcome (p=0.49). CONCLUSIONElevated serum BUN on admission, persistent tachycardia and need for fluid resuscitation were associated with increase LOS in pediatric AP. Daily total fluid intake above recommended maintenance did not reduce LOS. |
Author | Lauzon, Steven D Arbizu, Ricardo A Quiros, J Antonio Jump, Candi Baker, Susan S Shahein, Abdul R |
AuthorAffiliation | 1 Division of Pediatric Gastroenterology and Nutrition, Children's Hospital of Arkansas, Little Rock, AR, USA 2 Department of Pediatrics, University at Buffalo, Buffalo, NY, USA 3 Division of Pediatric Gastroenterology and Nutrition, Medical University of South Carolina Children's Hospital, Charleston, SC, USA 4 Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA |
AuthorAffiliation_xml | – name: 3 Division of Pediatric Gastroenterology and Nutrition, Medical University of South Carolina Children's Hospital, Charleston, SC, USA – name: 2 Department of Pediatrics, University at Buffalo, Buffalo, NY, USA – name: 4 Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, USA – name: 1 Division of Pediatric Gastroenterology and Nutrition, Children's Hospital of Arkansas, Little Rock, AR, USA |
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References | Brotanek (10.5223/pghn.2020.23.4.356_ref33) 2007; 120 Hack (10.5223/pghn.2020.23.4.356_ref15) 2001; 29 Martínez (10.5223/pghn.2020.23.4.356_ref29) 2004; 4 Gloor (10.5223/pghn.2020.23.4.356_ref31) 2001; 88 Johnson (10.5223/pghn.2020.23.4.356_ref30) 2004; 4 Aggarwal (10.5223/pghn.2020.23.4.356_ref13) 2014; 20 Abu-El-Haija (10.5223/pghn.2020.23.4.356_ref5) 2018; 194 DeBanto (10.5223/pghn.2020.23.4.356_ref25) 2002; 97 Banks (10.5223/pghn.2020.23.4.356_ref27) 1997; 92 Ceneviva (10.5223/pghn.2020.23.4.356_ref20) 1998; 102 Szabo (10.5223/pghn.2020.23.4.356_ref26) 2016; 16 Kumar (10.5223/pghn.2020.23.4.356_ref6) 2016; 170 Gay (10.5223/pghn.2020.23.4.356_ref12) 2018; 67 Nathens (10.5223/pghn.2020.23.4.356_ref28) 2004; 32 Pant (10.5223/pghn.2020.23.4.356_ref11) 2016; 62 Eckerwall (10.5223/pghn.2020.23.4.356_ref17) 2006; 25 Mayer (10.5223/pghn.2020.23.4.356_ref14) 2000; 47 Halonen (10.5223/pghn.2020.23.4.356_ref32) 2000; 21 Nydegger (10.5223/pghn.2020.23.4.356_ref2) 2007; 22 Abu-El-Haija (10.5223/pghn.2020.23.4.356_ref8) 2014; 58 Perel (10.5223/pghn.2020.23.4.356_ref34) 2013 Park (10.5223/pghn.2020.23.4.356_ref3) 2009; 49 de-Madaria (10.5223/pghn.2020.23.4.356_ref16) 2011; 106 Ranson (10.5223/pghn.2020.23.4.356_ref19) 1974; 139 Mao (10.5223/pghn.2020.23.4.356_ref18) 2007; 45 Abu-El-Haija (10.5223/pghn.2020.23.4.356_ref36) 2018; 66 Goldstein (10.5223/pghn.2020.23.4.356_ref21) 2005; 6 Bai (10.5223/pghn.2020.23.4.356_ref10) 2011; 52 Granger (10.5223/pghn.2020.23.4.356_ref23) 2005; 24 Vitale (10.5223/pghn.2020.23.4.356_ref24) 2019; 48 Quiros (10.5223/pghn.2020.23.4.356_ref35) 2008; 9 Pant (10.5223/pghn.2020.23.4.356_ref4) 2014; 9 Abu-El-Haija (10.5223/pghn.2020.23.4.356_ref9) 2017; 64 Morinville (10.5223/pghn.2020.23.4.356_ref7) 2012; 55 Lin (10.5223/pghn.2020.23.4.356_ref22) 2017; 2017 Morinville (10.5223/pghn.2020.23.4.356_ref1) 2010; 39 |
References_xml | – volume: 39 start-page: 5 year: 2010 ident: 10.5223/pghn.2020.23.4.356_ref1 publication-title: Pancreas doi: 10.1097/MPA.0b013e3181baac47 contributor: fullname: Morinville – volume: 139 start-page: 69 year: 1974 ident: 10.5223/pghn.2020.23.4.356_ref19 publication-title: Surg Gynecol Obstet contributor: fullname: Ranson – volume: 170 start-page: 562 year: 2016 ident: 10.5223/pghn.2020.23.4.356_ref6 publication-title: JAMA Pediatr doi: 10.1001/jamapediatrics.2015.4955 contributor: fullname: Kumar – start-page: CD000567 issue: 2 year: 2013 ident: 10.5223/pghn.2020.23.4.356_ref34 publication-title: Cochrane Database Syst Rev contributor: fullname: Perel – volume: 52 start-page: 262 year: 2011 ident: 10.5223/pghn.2020.23.4.356_ref10 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0b013e3182061d75 contributor: fullname: Bai – volume: 106 start-page: 1843 year: 2011 ident: 10.5223/pghn.2020.23.4.356_ref16 publication-title: Am J Gastroenterol doi: 10.1038/ajg.2011.236 contributor: fullname: de-Madaria – volume: 25 start-page: 497 year: 2006 ident: 10.5223/pghn.2020.23.4.356_ref17 publication-title: Clin Nutr doi: 10.1016/j.clnu.2005.10.012 contributor: fullname: Eckerwall – volume: 48 start-page: 363 year: 2019 ident: 10.5223/pghn.2020.23.4.356_ref24 publication-title: Pancreas doi: 10.1097/MPA.0000000000001265 contributor: fullname: Vitale – volume: 92 start-page: 377 year: 1997 ident: 10.5223/pghn.2020.23.4.356_ref27 publication-title: Am J Gastroenterol contributor: fullname: Banks – volume: 21 start-page: 266 year: 2000 ident: 10.5223/pghn.2020.23.4.356_ref32 publication-title: Pancreas doi: 10.1097/00006676-200010000-00008 contributor: fullname: Halonen – volume: 66 start-page: 159 year: 2018 ident: 10.5223/pghn.2020.23.4.356_ref36 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0000000000001715 contributor: fullname: Abu-El-Haija – volume: 49 start-page: 316 year: 2009 ident: 10.5223/pghn.2020.23.4.356_ref3 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0b013e31818d7db3 contributor: fullname: Park – volume: 55 start-page: 261 year: 2012 ident: 10.5223/pghn.2020.23.4.356_ref7 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0b013e31824f1516 contributor: fullname: Morinville – volume: 62 start-page: 450 year: 2016 ident: 10.5223/pghn.2020.23.4.356_ref11 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0000000000001058 contributor: fullname: Pant – volume: 29 start-page: S21 issue: 7 Suppl year: 2001 ident: 10.5223/pghn.2020.23.4.356_ref15 publication-title: Crit Care Med doi: 10.1097/00003246-200107001-00011 contributor: fullname: Hack – volume: 97 start-page: 1726 year: 2002 ident: 10.5223/pghn.2020.23.4.356_ref25 publication-title: Am J Gastroenterol doi: 10.1111/j.1572-0241.2002.05833.x contributor: fullname: DeBanto – volume: 20 start-page: 18092 year: 2014 ident: 10.5223/pghn.2020.23.4.356_ref13 publication-title: World J Gastroenterol doi: 10.3748/wjg.v20.i48.18092 contributor: fullname: Aggarwal – volume: 120 start-page: 568 year: 2007 ident: 10.5223/pghn.2020.23.4.356_ref33 publication-title: Pediatrics doi: 10.1542/peds.2007-0572 contributor: fullname: Brotanek – volume: 22 start-page: 1313 year: 2007 ident: 10.5223/pghn.2020.23.4.356_ref2 publication-title: J Gastroenterol Hepatol doi: 10.1111/j.1440-1746.2007.04936.x contributor: fullname: Nydegger – volume: 4 start-page: 42 year: 2004 ident: 10.5223/pghn.2020.23.4.356_ref29 publication-title: Pancreatology doi: 10.1159/000077025 contributor: fullname: Martínez – volume: 58 start-page: 689 year: 2014 ident: 10.5223/pghn.2020.23.4.356_ref8 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0000000000000360 contributor: fullname: Abu-El-Haija – volume: 16 start-page: 358 year: 2016 ident: 10.5223/pghn.2020.23.4.356_ref26 publication-title: Pancreatology doi: 10.1016/j.pan.2016.03.002 contributor: fullname: Szabo – volume: 47 start-page: 546 year: 2000 ident: 10.5223/pghn.2020.23.4.356_ref14 publication-title: Gut doi: 10.1136/gut.47.4.546 contributor: fullname: Mayer – volume: 45 start-page: 1331 year: 2007 ident: 10.5223/pghn.2020.23.4.356_ref18 publication-title: Zhonghua Wai Ke Za Zhi contributor: fullname: Mao – volume: 6 start-page: 2 year: 2005 ident: 10.5223/pghn.2020.23.4.356_ref21 publication-title: Pediatr Crit Care Med doi: 10.1097/01.PCC.0000149131.72248.E6 contributor: fullname: Goldstein – volume: 2017 start-page: 9592831 year: 2017 ident: 10.5223/pghn.2020.23.4.356_ref22 publication-title: Can J Gastroenterol Hepatol doi: 10.1155/2017/9592831 contributor: fullname: Lin – volume: 32 start-page: 2524 year: 2004 ident: 10.5223/pghn.2020.23.4.356_ref28 publication-title: Crit Care Med doi: 10.1097/01.CCM.0000148222.09869.92 contributor: fullname: Nathens – volume: 9 start-page: 418 year: 2008 ident: 10.5223/pghn.2020.23.4.356_ref35 publication-title: Pediatr Crit Care Med doi: 10.1097/PCC.0b013e318172e99b contributor: fullname: Quiros – volume: 9 start-page: e95552 year: 2014 ident: 10.5223/pghn.2020.23.4.356_ref4 publication-title: PLoS One doi: 10.1371/journal.pone.0095552 contributor: fullname: Pant – volume: 64 start-page: 984 year: 2017 ident: 10.5223/pghn.2020.23.4.356_ref9 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0000000000001583 contributor: fullname: Abu-El-Haija – volume: 194 start-page: 147 year: 2018 ident: 10.5223/pghn.2020.23.4.356_ref5 publication-title: J Pediatr doi: 10.1016/j.jpeds.2017.09.061 contributor: fullname: Abu-El-Haija – volume: 102 start-page: e19 year: 1998 ident: 10.5223/pghn.2020.23.4.356_ref20 publication-title: Pediatrics doi: 10.1542/peds.102.2.e19 contributor: fullname: Ceneviva – volume: 24 start-page: 45 issue: Suppl 1 year: 2005 ident: 10.5223/pghn.2020.23.4.356_ref23 publication-title: Shock doi: 10.1097/01.shk.0000191413.94461.b0 contributor: fullname: Granger – volume: 88 start-page: 975 year: 2001 ident: 10.5223/pghn.2020.23.4.356_ref31 publication-title: Br J Surg doi: 10.1046/j.0007-1323.2001.01813.x contributor: fullname: Gloor – volume: 67 start-page: e30 year: 2018 ident: 10.5223/pghn.2020.23.4.356_ref12 publication-title: J Pediatr Gastroenterol Nutr doi: 10.1097/MPG.0000000000002033 contributor: fullname: Gay – volume: 4 start-page: 1 year: 2004 ident: 10.5223/pghn.2020.23.4.356_ref30 publication-title: Pancreatology doi: 10.1159/000077021 contributor: fullname: Johnson |
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Snippet | There have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed consensus... PURPOSEThere have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed... Purpose: There have been many efforts to develop generalizable severity markers in children with acute pancreatitis (AP). Expert opinion panels have developed... |
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Title | Impact of Clinical, Laboratory and Fluid Therapy Variables on Hospital Length of Stay for Children with Acute Pancreatitis |
URI | https://www.ncbi.nlm.nih.gov/pubmed/32704496 https://search.proquest.com/docview/2427301225 https://pubmed.ncbi.nlm.nih.gov/PMC7354873 https://www.kci.go.kr/kciportal/ci/sereArticleSearch/ciSereArtiView.kci?sereArticleSearchBean.artiId=ART002608818 |
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ispartofPNX | Pediatric Gastroenterology, 2020, Hepatology & Nutrition, 23(4), , pp.356-365 |
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