Functional organization and plasticity in the adult rat barrel cortex: moving out-of-the-box
Recent advances in functional imaging and neuronal recording techniques demonstrate that the spatial spread and amplitude of whisker functional representation in the somatosensory cortex of the adult rodent is extensive, but subject to modulations. One of the strongest modulators is naturalistic whi...
Saved in:
| Published in | Current opinion in neurobiology Vol. 16; no. 4; pp. 445 - 450 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
England
Elsevier Ltd
01.08.2006
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0959-4388 1873-6882 |
| DOI | 10.1016/j.conb.2006.06.001 |
Cover
| Abstract | Recent advances in functional imaging and neuronal recording techniques demonstrate that the spatial spread and amplitude of whisker functional representation in the somatosensory cortex of the adult rodent is extensive, but subject to modulations. One of the strongest modulators is naturalistic whisker use. In the cortices of rodents that have been transferred from their home cage to live for an extensive period in a naturalistic habitat, there is suppression of evoked neuronal responses accompanied by contraction and sharpening of receptive fields, and contraction and weakening of whisker functional representations. These unexpected characteristics also describe modulations of whisker functional representations in the cortex of a freely exploring rodent during short whisker-based explorations. These and related findings suggest that cortical modulations and plasticity could follow a ‘less is more’ strategy and, therefore, highlight how different cortical strategies could be utilized for different behavioral demands. |
|---|---|
| AbstractList | Recent advances in functional imaging and neuronal recording techniques demonstrate that the spatial spread and amplitude of whisker functional representation in the somatosensory cortex of the adult rodent is extensive, but subject to modulations. One of the strongest modulators is naturalistic whisker use. In the cortices of rodents that have been transferred from their home cage to live for an extensive period in a naturalistic habitat, there is suppression of evoked neuronal responses accompanied by contraction and sharpening of receptive fields, and contraction and weakening of whisker functional representations. These unexpected characteristics also describe modulations of whisker functional representations in the cortex of a freely exploring rodent during short whisker-based explorations. These and related findings suggest that cortical modulations and plasticity could follow a 'less is more' strategy and, therefore, highlight how different cortical strategies could be utilized for different behavioral demands.Recent advances in functional imaging and neuronal recording techniques demonstrate that the spatial spread and amplitude of whisker functional representation in the somatosensory cortex of the adult rodent is extensive, but subject to modulations. One of the strongest modulators is naturalistic whisker use. In the cortices of rodents that have been transferred from their home cage to live for an extensive period in a naturalistic habitat, there is suppression of evoked neuronal responses accompanied by contraction and sharpening of receptive fields, and contraction and weakening of whisker functional representations. These unexpected characteristics also describe modulations of whisker functional representations in the cortex of a freely exploring rodent during short whisker-based explorations. These and related findings suggest that cortical modulations and plasticity could follow a 'less is more' strategy and, therefore, highlight how different cortical strategies could be utilized for different behavioral demands. Recent advances in functional imaging and neuronal recording techniques demonstrate that the spatial spread and amplitude of whisker functional representation in the somatosensory cortex of the adult rodent is extensive, but subject to modulations. One of the strongest modulators is naturalistic whisker use. In the cortices of rodents that have been transferred from their home cage to live for an extensive period in a naturalistic habitat, there is suppression of evoked neuronal responses accompanied by contraction and sharpening of receptive fields, and contraction and weakening of whisker functional representations. These unexpected characteristics also describe modulations of whisker functional representations in the cortex of a freely exploring rodent during short whisker-based explorations. These and related findings suggest that cortical modulations and plasticity could follow a ‘less is more’ strategy and, therefore, highlight how different cortical strategies could be utilized for different behavioral demands. |
| Author | Frostig, Ron D |
| Author_xml | – sequence: 1 givenname: Ron D surname: Frostig fullname: Frostig, Ron D email: rfrostig@uci.edu organization: Neurobiology and Behavior, Biomedical Engineering, and the Center for the Neurobiology of Learning and Memory, University of California, Irvine, CA 92697-4550, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/16822663$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkUFvFCEYhompsdvqH_BgOHmbLQwMMI0X01g1adJLjyaEYT4qKwsrME3XX-9Mt3rooU2-hJA8z3t43xN0FFMEhN5TsqaEirPN2qY4rFtCxHo5Ql-hFVWSNUKp9gitSN_1DWdKHaOTUjZkBplib9AxFapthWAr9ONyirb6FE3AKd-a6P-Y5YtNHPEumFK99XWPfcT1J2AzTqHibCoeTM4QsE25wv053qY7H29xmmqTXDOjzZDu36LXzoQC7x7fU3Rz-eXm4ltzdf31-8Xnq8ZyJmpjnTW9VaTve9o67sigpBgd62gnnHRWGKYGSiQDCs5INTDeEkZ4Rzm3XLJT9PEQu8vp9wSl6q0vFkIwEdJUtFCSStb1L4JUtly1D4kfHsFp2MKod9lvTd7rf73NgDoANqdSMjg9t_RQXM3GB02JXibSG71MpJeJ9HKEzmr7RP2f_pz06SDBXOOdh6yL9RAtjD6DrXpM_nn9_Ilug4_emvAL9i_JfwFSKb2O |
| CitedBy_id | crossref_primary_10_1152_jn_00349_2022 crossref_primary_10_1186_s12974_016_0609_4 crossref_primary_10_1007_s00702_007_0761_1 crossref_primary_10_1177_1073858409336092 crossref_primary_10_1177_1073858408317066 crossref_primary_10_1089_neu_2009_1237 crossref_primary_10_1111_j_1460_9568_2008_06313_x crossref_primary_10_1016_j_neuroscience_2009_07_065 crossref_primary_10_1117_1_NPh_2_4_041403 crossref_primary_10_3389_fncir_2018_00042 crossref_primary_10_1002_jnr_22008 crossref_primary_10_1016_j_brainres_2011_02_068 crossref_primary_10_1111_mam_12253 crossref_primary_10_1523_JNEUROSCI_4074_08_2008 crossref_primary_10_1097_PRS_0b013e318191bca2 crossref_primary_10_1016_j_brainres_2008_11_022 crossref_primary_10_1038_nrn3667 crossref_primary_10_1016_j_neuroscience_2011_10_040 crossref_primary_10_1371_journal_pone_0011270 crossref_primary_10_1146_annurev_cellbio_100814_125353 crossref_primary_10_3389_fnana_2014_00093 crossref_primary_10_1523_JNEUROSCI_1841_12_2012 crossref_primary_10_1016_j_neuroimage_2011_09_050 crossref_primary_10_1093_cercor_bhp281 crossref_primary_10_1556_APhysiol_95_2008_3_1 crossref_primary_10_1177_0022034510373767 crossref_primary_10_1093_cercor_bht241 crossref_primary_10_1101_lm_034827_114 crossref_primary_10_1007_s00429_021_02424_3 crossref_primary_10_1016_j_neubiorev_2022_104811 crossref_primary_10_1007_s00429_017_1472_5 crossref_primary_10_1016_j_brainres_2011_08_026 crossref_primary_10_1016_j_neuroscience_2010_07_029 crossref_primary_10_1016_j_neuroimage_2010_06_022 |
| Cites_doi | 10.1038/nrn1536 10.1523/JNEUROSCI.19-22-10164.1999 10.1523/JNEUROSCI.21-24-09944.2001 10.1016/j.neuroimage.2005.02.030 10.1113/jphysiol.2002.016857 10.1152/jn.00917.2004 10.1016/S0896-6273(02)00663-3 10.1152/jn.00912.2004 10.1016/S1053-8119(03)00086-7 10.1016/S0896-6273(03)00403-3 10.1038/nature02469 10.1523/JNEUROSCI.19-20-09117.1999 10.1523/JNEUROSCI.20-16-06241.2000 10.1152/jn.1998.80.6.2882 10.1152/jn.1999.81.3.1171 10.1016/j.neuron.2006.03.043 10.1126/science.1115807 10.1080/08990220500084990 10.1152/jn.00113.2004 10.1016/S0896-6273(03)00853-5 10.1016/S0959-4388(00)00112-4 10.1523/JNEUROSCI.12-01-00153.1992 10.1523/JNEUROSCI.4526-03.2004 10.1016/0301-0082(92)90013-5 10.1523/JNEUROSCI.23-04-01298.2003 10.1523/JNEUROSCI.22-22-09651.2002 10.1523/JNEUROSCI.19-17-07603.1999 10.1073/pnas.0407789102 10.1152/jn.00905.2003 10.1113/jphysiol.2002.018465 10.1523/JNEUROSCI.23-08-03100.2003 10.1073/pnas.0308470101 10.1016/j.neuron.2005.10.013 10.1523/JNEUROSCI.20-16-06135.2000 10.1097/00004647-200203000-00013 10.1113/jphysiol.2003.040709 10.1111/j.1460-9568.2004.03735.x 10.1046/j.0953-816x.2002.01898.x 10.1093/cercor/9.4.348 10.1152/jn.00906.2003 10.1152/jn.00860.2002 10.1016/S0165-0270(02)00185-1 10.1016/j.pneurobio.2004.09.002 10.1126/science.1093318 10.1113/jphysiol.2003.044222 10.1016/j.neuroscience.2004.06.004 10.1016/S0896-6273(00)81117-4 10.1523/JNEUROSCI.23-32-10190.2003 |
| ContentType | Journal Article |
| Copyright | 2006 Elsevier Ltd |
| Copyright_xml | – notice: 2006 Elsevier Ltd |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7QG 7TK 7X8 |
| DOI | 10.1016/j.conb.2006.06.001 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Animal Behavior Abstracts Neurosciences Abstracts MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Neurosciences Abstracts Animal Behavior Abstracts MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE Neurosciences Abstracts |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Anatomy & Physiology |
| EISSN | 1873-6882 |
| EndPage | 450 |
| ExternalDocumentID | 16822663 10_1016_j_conb_2006_06_001 S0959438806000778 |
| Genre | Journal Article Review Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: NINDS NIH HHS grantid: NS-43165 – fundername: NINDS NIH HHS grantid: NS-48350 |
| GroupedDBID | --- --K --M -DZ -~X .1- .FO .GJ .~1 0R~ 1B1 1CY 1P~ 1RT 1~. 1~5 29F 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 8P~ 9JM AABNK AAEDT AAEDW AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AATTM AAXKI AAXLA AAXUO AAYWO ABCQJ ABFRF ABIVO ABJNI ABMAC ABOCM ABTEW ABWVN ABXDB ACDAQ ACGFO ACGFS ACIUM ACNCT ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADIYS ADMUD ADNMO AEBSH AEFWE AEIPS AEKER AENEX AEUPX AEVXI AFJKZ AFPUW AFRHN AFTJW AFXIZ AGCQF AGHFR AGQPQ AGUBO AGWIK AGYEJ AHHHB AIEXJ AIGII AIIUN AIKHN AITUG AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU APXCP ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC CAG COF CS3 DU5 EBS EFJIC EFKBS EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HMQ HVGLF HZ~ IHE J1W KOM L7B M2V M41 MO0 MOBAO N9A O-L O9- OAUVE OP~ OZT P-8 P-9 P2P PC. Q38 R2- ROL RPZ SCC SDF SDG SDP SES SEW SNS SPCBC SSN SSZ T5K WUQ Z5R ZGI ~G- AACTN AADPK AAIAV ABYKQ AFCTW AFKWA AJBFU AJOXV AMFUW EFLBG RIG ZA5 AAYXX AGRNS BNPGV CITATION SSH CGR CUY CVF ECM EIF NPM PKN 7QG 7TK 7X8 |
| ID | FETCH-LOGICAL-c436t-cfca9c8099912f4f0b876df35156f7fc6a38b1073e1efa78b34203045144c473 |
| IEDL.DBID | .~1 |
| ISSN | 0959-4388 |
| IngestDate | Thu Sep 04 21:58:24 EDT 2025 Fri Sep 05 03:32:50 EDT 2025 Wed Feb 19 01:46:31 EST 2025 Thu Apr 24 23:08:22 EDT 2025 Tue Jul 01 03:03:13 EDT 2025 Fri Feb 23 02:19:13 EST 2024 Tue Aug 26 17:40:22 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Language | English |
| License | https://www.elsevier.com/tdm/userlicense/1.0 |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c436t-cfca9c8099912f4f0b876df35156f7fc6a38b1073e1efa78b34203045144c473 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 ObjectType-Article-1 ObjectType-Feature-2 ObjectType-Review-3 |
| PMID | 16822663 |
| PQID | 17248247 |
| PQPubID | 23462 |
| PageCount | 6 |
| ParticipantIDs | proquest_miscellaneous_68717359 proquest_miscellaneous_17248247 pubmed_primary_16822663 crossref_citationtrail_10_1016_j_conb_2006_06_001 crossref_primary_10_1016_j_conb_2006_06_001 elsevier_sciencedirect_doi_10_1016_j_conb_2006_06_001 elsevier_clinicalkey_doi_10_1016_j_conb_2006_06_001 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2006-08-01 |
| PublicationDateYYYYMMDD | 2006-08-01 |
| PublicationDate_xml | – month: 08 year: 2006 text: 2006-08-01 day: 01 |
| PublicationDecade | 2000 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | Current opinion in neurobiology |
| PublicationTitleAlternate | Curr Opin Neurobiol |
| PublicationYear | 2006 |
| Publisher | Elsevier Ltd |
| Publisher_xml | – name: Elsevier Ltd |
| References | Ghazanfar, Nicolelis (bib33) 1999; 9 Brecht, Sakmann (bib18) 2002; 543 Castro-Alamancos, Oldford (bib37) 2002; 541 Fox, Wong (bib2) 2005; 48 Rector, Carter, Volegov, George (bib29) 2005; 26 Grinvald, Hildesheim (bib15) 2004; 5 Petersen, Grinvald, Sakmann (bib14) 2003; 23 Erinjeri, Woolsey (bib23) 2002; 22 Kossut (bib42) 1992; 39 Knott, Quairiaux, Genoud, Welker (bib46) 2002; 34 Fanselow, Nicolelis (bib12) 1999; 19 Derdikman, Hildesheim, Ahissar, Arieli, Grinvald (bib13) 2003; 23 Devor, Ulbert, Dunn, Narayanan, Jones, Andermann, Boas, Dale (bib27) 2005; 102 Castro-Alamancos (bib38) 2004; 41 Welker, Rao, Dorfl, Melzer, van der Loos (bib45) 1992; 12 Polley, Kvasnak, Frostig (bib48) 2004; 429 Higley, Contreras (bib8) 2003; 23 Kida, Shimegi, Sato (bib11) 2005; 94 Brett-Green, Paulsen, Staba, Fifkova, Barth (bib21) 2004; 91 Weber, Burger, Wyss, von Schulthess, Scheffold, Buck (bib31) 2004; 20 Castro-Alamancos (bib39) 2004; 74 Petersen, Diamond (bib34) 2000; 20 Ego-Stengel, Mello e Souza, Jacob, Shulz (bib10) 2005; 93 Feldman, Brecht (bib1) 2005; 310 Brett-Green, Chen-Bee, Frostig (bib22) 2001; 21 Polley, Chen-Bee, Frostig (bib47) 1999; 24 Erchova, Lebedev, Diamond (bib3) 2002; 15 Ferezou, Bolea, Petersen (bib36) 2006; 50 Masino (bib32) 2003; 89 Siucinska, Kossut (bib44) 2004; 127 Sheth, Nemoto, Guiou, Walker, Pouratian, Toga (bib24) 2003; 19 Dubroff, Stevens, Hitt, Maier, McCasland, Hodge (bib28) 2005; 22 Krupa, Wiest, Shuler, Laubach, Nicolelis (bib40) 2004; 304 Shimegi, Ichikawa, Akasaki, Sato (bib5) 1999; 19 Brecht, Roth, Sakmann (bib19) 2003; 553 Martin, Berwick, Johnston, Zheng, Martindale, Port, Redgrave, Mayhew (bib35) 2002; 120 Devor, Dunn, Andermann, Ulbert, Boas, Dale (bib26) 2003; 39 Shimegi, Akasaki, Ichikawa, Sato (bib6) 2000; 20 Fox, Glazewski, Schulze (bib43) 2000; 10 Higley, Contreras (bib9) 2005; 93 Zhu, Connors (bib17) 1999; 81 Sheth, Nemoto, Guiou, Walker, Pouratian, Hageman, Toga (bib25) 2004; 24 Castro-Alamancos (bib20) 2002; 22 Ganguly, Kleinfeld (bib41) 2004; 101 Kelly, Carvell, Kodger, Simons (bib4) 1999; 19 Moore, Nelson (bib16) 1998; 80 Shibuki, Hishida, Murakami, Kudoh, Kawaguchi, Watanabe, Watanabe, Kouuchi, Tanaka (bib30) 2003; 549 Webber, Stanley (bib7) 2004; 91 Fox (10.1016/j.conb.2006.06.001_bib2) 2005; 48 Castro-Alamancos (10.1016/j.conb.2006.06.001_bib38) 2004; 41 Erchova (10.1016/j.conb.2006.06.001_bib3) 2002; 15 Ghazanfar (10.1016/j.conb.2006.06.001_bib33) 1999; 9 Polley (10.1016/j.conb.2006.06.001_bib48_1) 2004; 429 Higley (10.1016/j.conb.2006.06.001_bib8) 2003; 23 Brecht (10.1016/j.conb.2006.06.001_bib18) 2002; 543 Ganguly (10.1016/j.conb.2006.06.001_bib41) 2004; 101 Castro-Alamancos (10.1016/j.conb.2006.06.001_bib37) 2002; 541 Weber (10.1016/j.conb.2006.06.001_bib31) 2004; 20 Welker (10.1016/j.conb.2006.06.001_bib45) 1992; 12 Knott (10.1016/j.conb.2006.06.001_bib46) 2002; 34 Devor (10.1016/j.conb.2006.06.001_bib26) 2003; 39 Petersen (10.1016/j.conb.2006.06.001_bib34) 2000; 20 Siucinska (10.1016/j.conb.2006.06.001_bib44) 2004; 127 Brett-Green (10.1016/j.conb.2006.06.001_bib22) 2001; 21 Derdikman (10.1016/j.conb.2006.06.001_bib13) 2003; 23 Brecht (10.1016/j.conb.2006.06.001_bib19) 2003; 553 Fanselow (10.1016/j.conb.2006.06.001_bib12) 1999; 19 Moore (10.1016/j.conb.2006.06.001_bib16) 1998; 80 Castro-Alamancos (10.1016/j.conb.2006.06.001_bib20) 2002; 22 Devor (10.1016/j.conb.2006.06.001_bib27) 2005; 102 Martin (10.1016/j.conb.2006.06.001_bib35) 2002; 120 Shimegi (10.1016/j.conb.2006.06.001_bib6) 2000; 20 Sheth (10.1016/j.conb.2006.06.001_bib25) 2004; 24 Dubroff (10.1016/j.conb.2006.06.001_bib28) 2005; 22 Shibuki (10.1016/j.conb.2006.06.001_bib30) 2003; 549 Rector (10.1016/j.conb.2006.06.001_bib29) 2005; 26 Grinvald (10.1016/j.conb.2006.06.001_bib15) 2004; 5 Ego-Stengel (10.1016/j.conb.2006.06.001_bib10) 2005; 93 Sheth (10.1016/j.conb.2006.06.001_bib24) 2003; 19 Kida (10.1016/j.conb.2006.06.001_bib11) 2005; 94 Kelly (10.1016/j.conb.2006.06.001_bib4) 1999; 19 Zhu (10.1016/j.conb.2006.06.001_bib17) 1999; 81 Kossut (10.1016/j.conb.2006.06.001_bib42) 1992; 39 Ferezou (10.1016/j.conb.2006.06.001_bib36_1) 2006; 50 Brett-Green (10.1016/j.conb.2006.06.001_bib21) 2004; 91 Erinjeri (10.1016/j.conb.2006.06.001_bib23) 2002; 22 Webber (10.1016/j.conb.2006.06.001_bib7) 2004; 91 Polley (10.1016/j.conb.2006.06.001_bib47) 1999; 24 Higley (10.1016/j.conb.2006.06.001_bib9) 2005; 93 Masino (10.1016/j.conb.2006.06.001_bib32) 2003; 89 Shimegi (10.1016/j.conb.2006.06.001_bib5) 1999; 19 Petersen (10.1016/j.conb.2006.06.001_bib14) 2003; 23 Krupa (10.1016/j.conb.2006.06.001_bib40) 2004; 304 Fox (10.1016/j.conb.2006.06.001_bib43) 2000; 10 Feldman (10.1016/j.conb.2006.06.001_bib1) 2005; 310 Castro-Alamancos (10.1016/j.conb.2006.06.001_bib39_1) 2004; 74 |
| References_xml | – volume: 20 start-page: 6241 year: 2000 end-page: 6248 ident: bib6 article-title: Physiological and anatomical organization of multiwhisker response interactions in the barrel cortex of rats publication-title: J Neurosci – volume: 89 start-page: 1702 year: 2003 end-page: 1712 ident: bib32 article-title: Quantitative comparison between functional imaging and single-unit spiking in rat somatosensory cortex publication-title: J Neurophysiol – volume: 20 start-page: 6135 year: 2000 end-page: 6143 ident: bib34 article-title: Spatial-temporal distribution of whisker-evoked activity in rat somatosensory cortex and the coding of stimulus location publication-title: J Neurosci – volume: 553 start-page: 243 year: 2003 end-page: 265 ident: bib19 article-title: Dynamic receptive fields of reconstructed pyramidal cells in layers 3 and 2 of rat somatosensory barrel cortex publication-title: J Physiol – volume: 24 start-page: 623 year: 1999 end-page: 637 ident: bib47 article-title: Two directions of plasticity in the sensory-deprived adult cortex publication-title: Neuron – volume: 543 start-page: 49 year: 2002 end-page: 70 ident: bib18 article-title: Dynamic representation of whisker deflection by synaptic potentials in spiny stellate and pyramidal cells in the barrels and septa of layer 4 rat somatosensory cortex publication-title: J Physiol – volume: 101 start-page: 12348 year: 2004 end-page: 12353 ident: bib41 article-title: Goal-directed whisking increases phase-locking between vibrissa movement and electrical activity in primary sensory cortex in rat publication-title: Proc Natl Acad Sci USA – volume: 102 start-page: 3822 year: 2005 end-page: 3827 ident: bib27 article-title: Coupling of the cortical hemodynamic response to cortical and thalamic neuronal activity publication-title: Proc Natl Acad Sci USA – volume: 20 start-page: 2664 year: 2004 end-page: 2670 ident: bib31 article-title: Optical imaging of the spatiotemporal dynamics of cerebral blood flow and oxidative metabolism in the rat barrel cortex publication-title: Eur J Neurosci – volume: 9 start-page: 348 year: 1999 end-page: 361 ident: bib33 article-title: Spatiotemporal properties of layer V neurons of the rat primary somatosensory cortex publication-title: Cereb Cortex – volume: 22 start-page: 9651 year: 2002 end-page: 9655 ident: bib20 article-title: Role of thalamocortical sensory suppression during arousal: focusing sensory inputs in neocortex publication-title: J Neurosci – volume: 541 start-page: 319 year: 2002 end-page: 331 ident: bib37 article-title: Cortical sensory suppression during arousal is due to the activity-dependent depression of thalamocortical synapses publication-title: J Physiol – volume: 80 start-page: 2882 year: 1998 end-page: 2892 ident: bib16 article-title: Spatio-temporal subthreshold receptive fields in the vibrissa representation of rat primary somatosensory cortex publication-title: J Neurophysiol – volume: 21 start-page: 9944 year: 2001 end-page: 9954 ident: bib22 article-title: Comparing the functional representations of central and border whiskers in rat primary somatosensory cortex publication-title: J Neurosci – volume: 22 start-page: 25 year: 2005 end-page: 35 ident: bib28 article-title: Use-dependent plasticity in barrel cortex: intrinsic signal imaging reveals functional expansion of spared whisker representation into adjacent deprived columns publication-title: Somatosens Mot Res – volume: 549 start-page: 919 year: 2003 end-page: 927 ident: bib30 article-title: Dynamic imaging of somatosensory cortical activity in the rat visualized by flavoprotein autofluorescence publication-title: J Physiol – volume: 94 start-page: 2004 year: 2005 end-page: 2018 ident: bib11 article-title: Similarity of direction tuning among responses to stimulation of different whiskers in neurons of rat barrel cortex publication-title: J Neurophysiol – volume: 10 start-page: 494 year: 2000 end-page: 497 ident: bib43 article-title: Plasticity and stability of somatosensory maps in thalamus and cortex publication-title: Curr Opin Neurobiol – volume: 81 start-page: 1171 year: 1999 end-page: 1183 ident: bib17 article-title: Intrinsic firing patterns and whisker-evoked synaptic responses of neurons in the rat barrel cortex publication-title: J Neurophysiol – volume: 127 start-page: 961 year: 2004 end-page: 971 ident: bib44 article-title: Experience-dependent changes in cortical whisker representation in the adult mouse: a 2-deoxyglucose study publication-title: Neuroscience – volume: 74 start-page: 213 year: 2004 end-page: 247 ident: bib39 article-title: Dynamics of sensory thalamocortical synaptic networks during information processing states publication-title: Prog Neurobiol – volume: 19 start-page: 7603 year: 1999 end-page: 7616 ident: bib12 article-title: Behavioral modulation of tactile responses in the rat somatosensory system publication-title: J Neurosci – volume: 93 start-page: 1920 year: 2005 end-page: 1934 ident: bib9 article-title: Integration of synaptic responses to neighboring whiskers in rat barrel cortex in vivo publication-title: J Neurophysiol – volume: 93 start-page: 1450 year: 2005 end-page: 1467 ident: bib10 article-title: Spatiotemporal characteristics of neuronal sensory integration in the barrel cortex of the rat publication-title: J Neurophysiol – volume: 23 start-page: 1298 year: 2003 end-page: 1309 ident: bib14 article-title: Spatiotemporal dynamics of sensory responses in layer 2/3 of rat barrel cortex measured in vivo by voltage-sensitive dye imaging combined with whole-cell voltage recordings and neuron reconstructions publication-title: J Neurosci – volume: 50 start-page: 617 year: 2006 end-page: 629 ident: bib36 article-title: Visualizing the cortical representation of whisker touch: voltage-sensitive dye imaging in freely moving mice publication-title: Neuron – volume: 120 start-page: 25 year: 2002 end-page: 34 ident: bib35 article-title: Optical imaging spectroscopy in the unanaesthetised rat publication-title: J Neurosci Methods – volume: 304 start-page: 1989 year: 2004 end-page: 1992 ident: bib40 article-title: Layer-specific somatosensory cortical activation during active tactile discrimination publication-title: Science – volume: 48 start-page: 465 year: 2005 end-page: 477 ident: bib2 article-title: A comparison of experience-dependent plasticity in the visual and somatosensory systems publication-title: Neuron – volume: 91 start-page: 1327 year: 2004 end-page: 1336 ident: bib21 article-title: Two distinct regions of secondary somatosensory cortex in the rat: topographical organization and multisensory responses publication-title: J Neurophysiol – volume: 19 start-page: 9117 year: 1999 end-page: 9125 ident: bib4 article-title: Sensory loss by selected whisker removal produces immediate disinhibition in the somatosensory cortex of behaving rats publication-title: J Neurosci – volume: 12 start-page: 153 year: 1992 end-page: 170 ident: bib45 article-title: Plasticity in the barrel cortex of the adult mouse: effects of chronic stimulation upon deoxyglucose uptake in the behaving animal publication-title: J Neurosci – volume: 19 start-page: 10164 year: 1999 end-page: 10175 ident: bib5 article-title: Temporal characteristics of response integration evoked by multiple whisker stimulations in the barrel cortex of rats publication-title: J Neurosci – volume: 310 start-page: 810 year: 2005 end-page: 815 ident: bib1 article-title: Map plasticity in somatosensory cortex publication-title: Science – volume: 23 start-page: 10190 year: 2003 end-page: 10200 ident: bib8 article-title: Nonlinear integration of sensory responses in the rat barrel cortex: an intracellular study in vivo publication-title: J Neurosci – volume: 24 start-page: 634 year: 2004 end-page: 641 ident: bib25 article-title: Columnar specificity of microvascular oxygenation and volume responses: implications for functional brain mapping publication-title: J Neurosci – volume: 22 start-page: 353 year: 2002 end-page: 360 ident: bib23 article-title: Spatial integration of vascular changes with neural activity in mouse cortex publication-title: J Cereb Blood Flow Metab – volume: 34 start-page: 265 year: 2002 end-page: 273 ident: bib46 article-title: Formation of dendritic spines with GABAergic synapses induced by whisker stimulation in adult mice publication-title: Neuron – volume: 23 start-page: 3100 year: 2003 end-page: 3105 ident: bib13 article-title: Imaging spatiotemporal dynamics of surround inhibition in the barrels somatosensory cortex publication-title: J Neurosci – volume: 429 start-page: 67 year: 2004 end-page: 71 ident: bib48 article-title: Naturalistic experience transforms sensory maps in the adult cortex of caged animals publication-title: Nature – volume: 91 start-page: 2010 year: 2004 end-page: 2022 ident: bib7 article-title: Nonlinear encoding of tactile patterns in the barrel cortex publication-title: J Neurophysiol – volume: 15 start-page: 744 year: 2002 end-page: 752 ident: bib3 article-title: Somatosensory cortical neuronal population activity across states of anaesthesia publication-title: Eur J Neurosci – volume: 19 start-page: 884 year: 2003 end-page: 894 ident: bib24 article-title: Evaluation of coupling between optical intrinsic signals and neuronal activity in rat somatosensory cortex publication-title: Neuroimage – volume: 41 start-page: 455 year: 2004 end-page: 464 ident: bib38 article-title: Absence of rapid sensory adaptation in neocortex during information processing states publication-title: Neuron – volume: 26 start-page: 619 year: 2005 end-page: 627 ident: bib29 article-title: Spatio-temporal mapping of rat whisker barrels with fast scattered light signals publication-title: Neuroimage – volume: 39 start-page: 353 year: 2003 end-page: 359 ident: bib26 article-title: Coupling of total hemoglobin concentration, oxygenation, and neural activity in rat somatosensory cortex publication-title: Neuron – volume: 39 start-page: 389 year: 1992 end-page: 422 ident: bib42 article-title: Plasticity of the barrel cortex neurons publication-title: Prog Neurobiol – volume: 5 start-page: 874 year: 2004 end-page: 885 ident: bib15 article-title: VSDI: a new era in functional imaging of cortical dynamics publication-title: Nat Rev Neurosci – volume: 5 start-page: 874 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib15 article-title: VSDI: a new era in functional imaging of cortical dynamics publication-title: Nat Rev Neurosci doi: 10.1038/nrn1536 – volume: 19 start-page: 10164 year: 1999 ident: 10.1016/j.conb.2006.06.001_bib5 article-title: Temporal characteristics of response integration evoked by multiple whisker stimulations in the barrel cortex of rats publication-title: J Neurosci doi: 10.1523/JNEUROSCI.19-22-10164.1999 – volume: 21 start-page: 9944 year: 2001 ident: 10.1016/j.conb.2006.06.001_bib22 article-title: Comparing the functional representations of central and border whiskers in rat primary somatosensory cortex publication-title: J Neurosci doi: 10.1523/JNEUROSCI.21-24-09944.2001 – volume: 26 start-page: 619 year: 2005 ident: 10.1016/j.conb.2006.06.001_bib29 article-title: Spatio-temporal mapping of rat whisker barrels with fast scattered light signals publication-title: Neuroimage doi: 10.1016/j.neuroimage.2005.02.030 – volume: 541 start-page: 319 year: 2002 ident: 10.1016/j.conb.2006.06.001_bib37 article-title: Cortical sensory suppression during arousal is due to the activity-dependent depression of thalamocortical synapses publication-title: J Physiol doi: 10.1113/jphysiol.2002.016857 – volume: 93 start-page: 1920 year: 2005 ident: 10.1016/j.conb.2006.06.001_bib9 article-title: Integration of synaptic responses to neighboring whiskers in rat barrel cortex in vivo publication-title: J Neurophysiol doi: 10.1152/jn.00917.2004 – volume: 34 start-page: 265 year: 2002 ident: 10.1016/j.conb.2006.06.001_bib46 article-title: Formation of dendritic spines with GABAergic synapses induced by whisker stimulation in adult mice publication-title: Neuron doi: 10.1016/S0896-6273(02)00663-3 – volume: 93 start-page: 1450 year: 2005 ident: 10.1016/j.conb.2006.06.001_bib10 article-title: Spatiotemporal characteristics of neuronal sensory integration in the barrel cortex of the rat publication-title: J Neurophysiol doi: 10.1152/jn.00912.2004 – volume: 19 start-page: 884 year: 2003 ident: 10.1016/j.conb.2006.06.001_bib24 article-title: Evaluation of coupling between optical intrinsic signals and neuronal activity in rat somatosensory cortex publication-title: Neuroimage doi: 10.1016/S1053-8119(03)00086-7 – volume: 39 start-page: 353 year: 2003 ident: 10.1016/j.conb.2006.06.001_bib26 article-title: Coupling of total hemoglobin concentration, oxygenation, and neural activity in rat somatosensory cortex publication-title: Neuron doi: 10.1016/S0896-6273(03)00403-3 – volume: 429 start-page: 67 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib48_1 article-title: Naturalistic experience transforms sensory maps in the adult cortex of caged animals publication-title: Nature doi: 10.1038/nature02469 – volume: 19 start-page: 9117 year: 1999 ident: 10.1016/j.conb.2006.06.001_bib4 article-title: Sensory loss by selected whisker removal produces immediate disinhibition in the somatosensory cortex of behaving rats publication-title: J Neurosci doi: 10.1523/JNEUROSCI.19-20-09117.1999 – volume: 20 start-page: 6241 year: 2000 ident: 10.1016/j.conb.2006.06.001_bib6 article-title: Physiological and anatomical organization of multiwhisker response interactions in the barrel cortex of rats publication-title: J Neurosci doi: 10.1523/JNEUROSCI.20-16-06241.2000 – volume: 80 start-page: 2882 year: 1998 ident: 10.1016/j.conb.2006.06.001_bib16 article-title: Spatio-temporal subthreshold receptive fields in the vibrissa representation of rat primary somatosensory cortex publication-title: J Neurophysiol doi: 10.1152/jn.1998.80.6.2882 – volume: 81 start-page: 1171 year: 1999 ident: 10.1016/j.conb.2006.06.001_bib17 article-title: Intrinsic firing patterns and whisker-evoked synaptic responses of neurons in the rat barrel cortex publication-title: J Neurophysiol doi: 10.1152/jn.1999.81.3.1171 – volume: 50 start-page: 617 year: 2006 ident: 10.1016/j.conb.2006.06.001_bib36_1 article-title: Visualizing the cortical representation of whisker touch: voltage-sensitive dye imaging in freely moving mice publication-title: Neuron doi: 10.1016/j.neuron.2006.03.043 – volume: 310 start-page: 810 year: 2005 ident: 10.1016/j.conb.2006.06.001_bib1 article-title: Map plasticity in somatosensory cortex publication-title: Science doi: 10.1126/science.1115807 – volume: 22 start-page: 25 year: 2005 ident: 10.1016/j.conb.2006.06.001_bib28 article-title: Use-dependent plasticity in barrel cortex: intrinsic signal imaging reveals functional expansion of spared whisker representation into adjacent deprived columns publication-title: Somatosens Mot Res doi: 10.1080/08990220500084990 – volume: 94 start-page: 2004 year: 2005 ident: 10.1016/j.conb.2006.06.001_bib11 article-title: Similarity of direction tuning among responses to stimulation of different whiskers in neurons of rat barrel cortex publication-title: J Neurophysiol doi: 10.1152/jn.00113.2004 – volume: 41 start-page: 455 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib38 article-title: Absence of rapid sensory adaptation in neocortex during information processing states publication-title: Neuron doi: 10.1016/S0896-6273(03)00853-5 – volume: 10 start-page: 494 year: 2000 ident: 10.1016/j.conb.2006.06.001_bib43 article-title: Plasticity and stability of somatosensory maps in thalamus and cortex publication-title: Curr Opin Neurobiol doi: 10.1016/S0959-4388(00)00112-4 – volume: 12 start-page: 153 year: 1992 ident: 10.1016/j.conb.2006.06.001_bib45 article-title: Plasticity in the barrel cortex of the adult mouse: effects of chronic stimulation upon deoxyglucose uptake in the behaving animal publication-title: J Neurosci doi: 10.1523/JNEUROSCI.12-01-00153.1992 – volume: 24 start-page: 634 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib25 article-title: Columnar specificity of microvascular oxygenation and volume responses: implications for functional brain mapping publication-title: J Neurosci doi: 10.1523/JNEUROSCI.4526-03.2004 – volume: 39 start-page: 389 year: 1992 ident: 10.1016/j.conb.2006.06.001_bib42 article-title: Plasticity of the barrel cortex neurons publication-title: Prog Neurobiol doi: 10.1016/0301-0082(92)90013-5 – volume: 23 start-page: 1298 year: 2003 ident: 10.1016/j.conb.2006.06.001_bib14 article-title: Spatiotemporal dynamics of sensory responses in layer 2/3 of rat barrel cortex measured in vivo by voltage-sensitive dye imaging combined with whole-cell voltage recordings and neuron reconstructions publication-title: J Neurosci doi: 10.1523/JNEUROSCI.23-04-01298.2003 – volume: 22 start-page: 9651 year: 2002 ident: 10.1016/j.conb.2006.06.001_bib20 article-title: Role of thalamocortical sensory suppression during arousal: focusing sensory inputs in neocortex publication-title: J Neurosci doi: 10.1523/JNEUROSCI.22-22-09651.2002 – volume: 19 start-page: 7603 year: 1999 ident: 10.1016/j.conb.2006.06.001_bib12 article-title: Behavioral modulation of tactile responses in the rat somatosensory system publication-title: J Neurosci doi: 10.1523/JNEUROSCI.19-17-07603.1999 – volume: 102 start-page: 3822 year: 2005 ident: 10.1016/j.conb.2006.06.001_bib27 article-title: Coupling of the cortical hemodynamic response to cortical and thalamic neuronal activity publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0407789102 – volume: 91 start-page: 1327 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib21 article-title: Two distinct regions of secondary somatosensory cortex in the rat: topographical organization and multisensory responses publication-title: J Neurophysiol doi: 10.1152/jn.00905.2003 – volume: 543 start-page: 49 year: 2002 ident: 10.1016/j.conb.2006.06.001_bib18 article-title: Dynamic representation of whisker deflection by synaptic potentials in spiny stellate and pyramidal cells in the barrels and septa of layer 4 rat somatosensory cortex publication-title: J Physiol doi: 10.1113/jphysiol.2002.018465 – volume: 23 start-page: 3100 year: 2003 ident: 10.1016/j.conb.2006.06.001_bib13 article-title: Imaging spatiotemporal dynamics of surround inhibition in the barrels somatosensory cortex publication-title: J Neurosci doi: 10.1523/JNEUROSCI.23-08-03100.2003 – volume: 101 start-page: 12348 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib41 article-title: Goal-directed whisking increases phase-locking between vibrissa movement and electrical activity in primary sensory cortex in rat publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0308470101 – volume: 48 start-page: 465 year: 2005 ident: 10.1016/j.conb.2006.06.001_bib2 article-title: A comparison of experience-dependent plasticity in the visual and somatosensory systems publication-title: Neuron doi: 10.1016/j.neuron.2005.10.013 – volume: 20 start-page: 6135 year: 2000 ident: 10.1016/j.conb.2006.06.001_bib34 article-title: Spatial-temporal distribution of whisker-evoked activity in rat somatosensory cortex and the coding of stimulus location publication-title: J Neurosci doi: 10.1523/JNEUROSCI.20-16-06135.2000 – volume: 22 start-page: 353 year: 2002 ident: 10.1016/j.conb.2006.06.001_bib23 article-title: Spatial integration of vascular changes with neural activity in mouse cortex publication-title: J Cereb Blood Flow Metab doi: 10.1097/00004647-200203000-00013 – volume: 549 start-page: 919 year: 2003 ident: 10.1016/j.conb.2006.06.001_bib30 article-title: Dynamic imaging of somatosensory cortical activity in the rat visualized by flavoprotein autofluorescence publication-title: J Physiol doi: 10.1113/jphysiol.2003.040709 – volume: 20 start-page: 2664 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib31 article-title: Optical imaging of the spatiotemporal dynamics of cerebral blood flow and oxidative metabolism in the rat barrel cortex publication-title: Eur J Neurosci doi: 10.1111/j.1460-9568.2004.03735.x – volume: 15 start-page: 744 year: 2002 ident: 10.1016/j.conb.2006.06.001_bib3 article-title: Somatosensory cortical neuronal population activity across states of anaesthesia publication-title: Eur J Neurosci doi: 10.1046/j.0953-816x.2002.01898.x – volume: 9 start-page: 348 year: 1999 ident: 10.1016/j.conb.2006.06.001_bib33 article-title: Spatiotemporal properties of layer V neurons of the rat primary somatosensory cortex publication-title: Cereb Cortex doi: 10.1093/cercor/9.4.348 – volume: 91 start-page: 2010 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib7 article-title: Nonlinear encoding of tactile patterns in the barrel cortex publication-title: J Neurophysiol doi: 10.1152/jn.00906.2003 – volume: 89 start-page: 1702 year: 2003 ident: 10.1016/j.conb.2006.06.001_bib32 article-title: Quantitative comparison between functional imaging and single-unit spiking in rat somatosensory cortex publication-title: J Neurophysiol doi: 10.1152/jn.00860.2002 – volume: 120 start-page: 25 year: 2002 ident: 10.1016/j.conb.2006.06.001_bib35 article-title: Optical imaging spectroscopy in the unanaesthetised rat publication-title: J Neurosci Methods doi: 10.1016/S0165-0270(02)00185-1 – volume: 74 start-page: 213 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib39_1 article-title: Dynamics of sensory thalamocortical synaptic networks during information processing states publication-title: Prog Neurobiol doi: 10.1016/j.pneurobio.2004.09.002 – volume: 304 start-page: 1989 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib40 article-title: Layer-specific somatosensory cortical activation during active tactile discrimination publication-title: Science doi: 10.1126/science.1093318 – volume: 553 start-page: 243 year: 2003 ident: 10.1016/j.conb.2006.06.001_bib19 article-title: Dynamic receptive fields of reconstructed pyramidal cells in layers 3 and 2 of rat somatosensory barrel cortex publication-title: J Physiol doi: 10.1113/jphysiol.2003.044222 – volume: 127 start-page: 961 year: 2004 ident: 10.1016/j.conb.2006.06.001_bib44 article-title: Experience-dependent changes in cortical whisker representation in the adult mouse: a 2-deoxyglucose study publication-title: Neuroscience doi: 10.1016/j.neuroscience.2004.06.004 – volume: 24 start-page: 623 year: 1999 ident: 10.1016/j.conb.2006.06.001_bib47 article-title: Two directions of plasticity in the sensory-deprived adult cortex publication-title: Neuron doi: 10.1016/S0896-6273(00)81117-4 – volume: 23 start-page: 10190 year: 2003 ident: 10.1016/j.conb.2006.06.001_bib8 article-title: Nonlinear integration of sensory responses in the rat barrel cortex: an intracellular study in vivo publication-title: J Neurosci doi: 10.1523/JNEUROSCI.23-32-10190.2003 |
| SSID | ssj0006383 |
| Score | 2.0502515 |
| SecondaryResourceType | review_article |
| Snippet | Recent advances in functional imaging and neuronal recording techniques demonstrate that the spatial spread and amplitude of whisker functional representation... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 445 |
| SubjectTerms | Action Potentials - physiology Afferent Pathways - physiology Animals Exploratory Behavior - physiology Mechanoreceptors - physiology Movement - physiology Neuronal Plasticity - physiology Neurons, Afferent - physiology Rats Somatosensory Cortex - physiology Touch - physiology Vibrissae - physiology |
| Title | Functional organization and plasticity in the adult rat barrel cortex: moving out-of-the-box |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0959438806000778 https://dx.doi.org/10.1016/j.conb.2006.06.001 https://www.ncbi.nlm.nih.gov/pubmed/16822663 https://www.proquest.com/docview/17248247 https://www.proquest.com/docview/68717359 |
| Volume | 16 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT-MwELYQXLigXZ5lefiAuCDTNnYde28VoioguCxIHJCi2LGlriCpIJXgwm_fGceB5VCQuEYeyXEmM9_MfDMm5ED1vXZOKMYL6SBA4QNmbE8zy71WhfYiL7BR-PJKjm_E-e3gdoGctL0wSKuMtr-x6cFaxyfdeJrd6WTS_YMZLIGzTCQ6uhQbfoVIUdePX99pHjKO4sR0F66OjTMNxwtCThMLEqEmMc85zQOfwQmNfpCViB7psNngT7LgylWyNiwhcn54oYc08DlDonyN3I3AZTWZPlr913FJ87KgUwDNyKeuX-ikpAACaRjEQUEfqEH27j21SMN9_k0fQs6BVrOaVZ7BUmaq53VyPTq9PhmzeJcCs4LLmllvc21VwIOJF75nwAwWngOckT71VuZcGQgFues7n6fKcJGEKioEXBZOdYMsllXptggVADCUTgCU93E0T6F6qfYQYidpniijeYf02zPMbJwzjtdd3GctoexvhueOF2DKrGHVdcjRm8y0mbLx6Wrefpqs7R8Fi5eBE_hUavAm9UHDvpTbb79-Br8e1lPy0lWzpwywn1CJSOevkApJDgPdIZuN2ry_nQRkBmhv-5u7-kWWm2QQUhF3yGL9OHO7AI9qsxf0f48sDc8uxlf_AP6YDUo |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT9wwELYoPbQXRKGPLRR8qHqp3N2NHcfmhhCrpQUu3UocKlmxY0tbQbKiWQku_e2dcRxoDwsS12gsOX7MfDPzzZiQj2octPdCMV5JDw4Kz5l1I80cD1pVOoiywkLhs3M5_SG-XuQXa-Sor4VBWmXS_Z1Oj9o6fRmm1Rwu5vPhd4xgCexlItHQFeoZeS5yXiCv78ufe56HTL04Md6F4qlypiN5gc9pU0YiJiVWWadV6DNaockm2UjwkR52M3xF1ny9RbYPa3Cdr27pJxoJnTFSvk1-TsBmdaE-2vxTcknLuqILQM1IqG5v6bymgAJp7MRB4UBQi_TdS-qQh3tzQK9i0IE2y5Y1gYEos83NazKbHM-Opiw9psCc4LJlLrhSOxUBYRZEGFnQg1XggGdkKIKTJVcWfEHuxz6UhbJcZDGNCh6XEwV_Q9brpvbvCBWAMJTOAJWPsTdPpUaFDuBjZ0WZKav5gIz7NTQuNRrH9y4uTc8o-2Vw3fEFTGk6Wt2AfL4bs-jabDwozfutMX0BKag8A1bgwVH53aj_jtij4_b73Tdw9zChUta-Wf42AP6EykSxWkIqZDnkekDedsfm_u8kQDOAe--fOKt98mI6Ozs1pyfn33bIyy4yhLzEXbLeXi_9B8BKrd2Ld-EvFscO3Q |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Functional+organization+and+plasticity+in+the+adult+rat+barrel+cortex%3A+moving+out-of-the-box&rft.jtitle=Current+opinion+in+neurobiology&rft.au=Frostig%2C+Ron+D&rft.date=2006-08-01&rft.issn=0959-4388&rft.volume=16&rft.issue=4&rft.spage=445&rft.epage=450&rft_id=info:doi/10.1016%2Fj.conb.2006.06.001&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0959-4388&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0959-4388&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0959-4388&client=summon |